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单个细胞凝胶电泳与染色体不稳定综合征 被引量：1

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摘要 介绍单个细胞凝胶电泳（SCGE）的原理及详细操作步骤。概括染色体不稳定（断裂）综合征中的常见疾病的临床特点，阐述各种疾病染色体不稳定的详细机制，以此说明SCGE用于染色体不稳定（断裂）综合征诊断的可能。简要总结SCGE在临床上的其他应用。
作者 魏述宁（综述） 齐军元（审校）
机构地区 中国医学科学院中国协和医科大学血液学研究所血液病医院
出处 《国际输血及血液学杂志》 CAS 2007年第6期537-539,共3页 International Journal of Blood Transfusion and Hematology
关键词 单个细胞凝胶电泳 染色体不稳定(断裂)综合征
分类号 R99 [医药卫生—毒理学]
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参考文献24

  • 1ostling O, Johanson KJ. Microelectrophoretic study of radiation induced DNA damages in individual cells. Biochem Biophys Res Commun, 1984, 123(1):291-298.
  • 2Burlinson B, Tiee RR, Speit G, et al. Fourth International Workgroup on Genotoxieity testing: results of the in vivo Comet assayworkgroup. Mutat Res, 2007, 627(1): 31-35.
  • 3Somorovska M, Szabova E, Vodicka P, et al. Biomonitoring of genotoxic risk in workers in a rubber factory: comparison of the Comet assay with cytogenetic methods and immunology. Mutat Res, 1999, 445(2): 181-192
  • 4Collins AR, Raslovd K, Somorovskd M, et al. DNA damage in diabetes : correlation with a clinical marker. Free Radic Biol Med, 1998, 25(3): 373-377.
  • 5Maluf SW, Erdtmann B. Genomic instability in Down syndrome and Fanconi anemia assessed by micronucleus analysis and single cell gel electrophoresis. Cancer Genet Cytogenet, 2001, 124(1):71-75.
  • 6Nadin SB, Vargas-Roig LM, Drago G, et al. DNA damage and repair in peripheral blood lymphocytes from healthy individuals and cancer patients : a pilot study on the implications in the clinical response to chemotherapy. Cancer Letters, 2006, 239(1) : 84-97.
  • 7齐军元,邵英起,刘永泽,刘强,郑以州,张凤奎,赵永成.单个细胞凝胶电泳分析在范可尼贫血诊断中的应用[J].中华血液学杂志,2006,27(10):690-693. 被引量：6
  • 8Taylor AMR. Chromosome instability syndrome. Best Praet Res Clin Haematol, 2001,14(3): 631-644.
  • 9Olive PL. The comet assay: An overview of techniques. Methods Mol Biol, 2002,203: 179-192.
  • 10Collins AR. The comet assay for DNA damage and repair. Mol Biotechnol, 2004, 26: 249-261.

二级参考文献3

  • 1Olive PL.The comet assay.An overview of techniques.Methods Mol Biol,2002,203:179-194.
  • 2Niedernhofer LJ,Lalai AS,Hoeijmakers JH.Fanooni amernia (cross)linked to DNA repair.Cell,2005,123:1191-1198.
  • 3Maluf SW,Erdtmann B.Genomic instrability in Down syndrome and Fanconi anemia assessed by micromucleus analysis and single-cell gel electrophoresis.Cancer Genet Cytogenet,2001,124:71-75.

共引文献5

同被引文献9

  • 1齐军元,邵英起,刘永泽,刘强,郑以州,张凤奎,赵永成.单个细胞凝胶电泳分析在范可尼贫血诊断中的应用[J].中华血液学杂志,2006,27(10):690-693. 被引量：6
  • 2申子瑜,李萍.临床实验室管理学.2版.北京:人民卫生出版社,2007: 17.
  • 3Auerbach AD. Fanconi anemia and its diagnosis. Mutat Res, 2009, 668:4-10.
  • 4Castella M, Pujol R, Callen E, et al. Chromosome fragility in patients with Fanconi anaemia: diagnostic implications and clinical impact. J Med Genet, 2011,48:242-250.
  • 5Vasquez MZ. Recommendations for safety testing with the in vivo comet assay. Murat Res, 2012, 747:142-156.
  • 6Mohseni-Meybodi A, Mozdarani H, Mozdarani S. DNA damage and repair of leukocytes from Fanconi anaemia patients, carriers and healthy individuals as measured by the alkaline comet assay. Mutagenesis, 2009, 24:67-73.
  • 7Cervenka J, Arthur D, Yasis C. Mitomycin C test for diagnostic differentiation of idiopathic aplastie anemia and Faneoni anemia. Pediatries, 1981, 67: 119-127.
  • 8Esmer C, Sanchez S, Ramos S, et al. DEB test for Fanconi anemia detection in patients with atypical phenotypes. Am J Med Genet A, 2004, 124A:35-39.
  • 9Maluf SW, Erdtmann B. Genomic instability in Down syndrome and Fanconi anemia assessed by micronucleus analysis and single- cell gel electrophoresis. Cancer Genet Cytogenet, 2001, 124:71- 75.

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国际输血及血液学杂志
2007年 第6期

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