13例肾癌病人介入治疗的临床分析

Clinical research of interventional treatment for 13 patients with kidney cancer

目的：观察肾癌肾动脉介入治疗的疗效及毒副反应。方法：2002年6月-2005年12月对13例不愿意接受手术或不能手术患者行肾动脉介入治疗,肾动脉内先注入化疗药物ADM40-60mg,MMC6-16mg,PDD40-60mg,然后注入无水酒精加碘油（1：1）10-20ml,最后用明胶海棉栓塞动脉主干,一个月做一次,2次结束后评价疗效。结果：13例病人治疗后,临床症状平均缓解率为90.32%,近期有效率为76.92%。毒副反应主要表现为腰痛加剧、发热、恶心、呕吐,经对症处理后,大部分于1周内,最长2周内缓解。结论：肾动脉灌注栓塞化疗是治疗不能手术肾癌的一疗效肯定,毒副反应可耐受的方法,值得临床推广应用。

Objective： To observe curative effect and side effect of interventional treatment of the kidney artery for patients with kidney cancer. Methods： From June 2002 to December 2005,13 patients who wouldnt like to be operated or cant accept operation were treated with interventional treatment of the kidney artery, Chemotherapy medicine： ADM40 -60mg, MMC6 -16mg and PDIM0 -60mg was injected in Kidney artery then absolute alcohol and lipiodot all together10-20ml （1：1） was injected; finally, use glutin sponge embolism to fill in the artery trunk. Once a month, the effect was evaluated twice later. Results： After the treatment, the average relief rate of clinical symptoms of the 13 patients was 90.20% ,and recent efficiency rate was 76.92%. The side effect inclut]ed： lumbago, fever, queasiness and vomit. But after treating, most symptoms relieved in one or two weeks. Conclusion： The chemotherapy priming embolism into kidney artery is an effective method, side effect is acceptable to treat kidney cancer who can