摘要
目的:探讨原发于肾脏肉瘤的临床组织发生、病理学特点、诊断、治疗及预后。方法:总结我院收治8例原发性肾肉瘤患者临床资料,对肾肉瘤标本进行常规HE、免疫组织化学染色观察。复习相关文献。结果:8例显微镜下表现、组织化学及免疫组织化学染色分别显示平滑肌肉瘤、脂肪肉瘤、粘液肉瘤、肾滑膜肉瘤、恶性纤维组织细胞瘤的特点。由病理确诊,术前仅1例怀疑肉瘤。结论:肾原发性肉瘤少见,临床诊断较困难,主要表现为患侧腰疼,肿块。依靠病理检查,配以免疫组织化学染色可确诊。手术切除病肾是唯一可行方法。预后甚差,化疗、放疗效果争议较大。
Objective: To investigate the clinical pathological characteristics ,prognosis of primary renal sarcoma. Methods:Eight cases of renal sarcoma in our hospital were analyzed and summarized. Nephrectomy were performed as the major medication . All the specimens were stained with histochemicial and immunohistochemical method , relat- ed literature were reviewed. Results: The histological types of the specimens were leiomyosarcoma, lipesarcoma, myxosarcoma synoviosarcoma,fibrous histiocytoma. Immunohistiochemical test was essential for the diagnosis of renal sarcoma. Conclusion: Renal sarcoma is a rare , highly malignant tumor with poor prognosis. Pain and palpable mass were the common symptoms. Early radical surgery is by now the optimal treatment, the effect of chemotherapy and radiotherapy was questionable.
出处
《现代肿瘤医学》
CAS
2007年第5期691-693,共3页
Journal of Modern Oncology
关键词
肾肿瘤
肉瘤
预后
kidney
sarcoma
pathology
prognosis