晚期非小细胞肺癌患者化疗后获得性肺炎的相关因素分析

Influential factors of post-chemotherapeutic acquired pneumonia of advanced non-small cell lung carcinoma patients

目的:探讨晚期非小细胞肺癌(NSCLC)化疗后获得性肺炎的影响因素。方法:选择8个可能对化疗后获得性肺炎产生影响的研究因素,进行Logistic回归分析,对我院2003年6月～2006年6月期间收治的76例晚期NSCLC化疗后获得性肺炎患者进行研究。结果:多因素非条件Logistic逐步回归分析显示:年龄超过60岁、吸烟史、基础疾病、肿瘤压迫气道、重度骨髓抑制是晚期NSCLC化疗后获得性肺炎的主要危险因素。结论:选择化疗方案时,应综合考虑以上因素,降低获得性肺炎的发生率。

Objective：To investigate the influential factor of post-chemotherapeutic acquired pneumonia of advanced non-small cell lung carcinoma（NSCLC）.Methods：Eight possible influencing factors were analyzed,data of the 76 post-chemotherapeutic acquired pneumonia of advanced NSCLC from June 2003 to June 2006 was conducted.Results：The risk factors were identified by multifactor noconditional logistic regression,including age older than 60,smoking,basic disease,oncothlipsis trachea,serious myelosuppression.Conclusion：It is necessary to choose suitable chemotherapy plan to decrease the incidence rate of acquired pneumonia for the patients of NSCLC.