膀胱鳞状细胞癌诊疗体会

The diagnosis and treatment of squamous cell carcinoma of bladder

目的:探讨膀胱鳞状细胞癌的病因、诊断与治疗。方法:回顾性分析8例膀胱鳞癌患者的临床资料,复习相关文献。结果:2例行膀胱部分切除术,6例行膀胱全切术,术后均行放疗或免疫疗法,行膀胱部分切除术者至今仍生存1例,为结合免疫治疗患者,1例死亡者由于恶性肿瘤转移。行膀胱全切术者6例,至今生存2例,3例死亡,此3例均由于恶性肿瘤多发转移,1例失访。结论:膀胱鳞癌的预后较差,大多数患者在被诊断时已属晚期,膀胱鳞癌的恶性程度较高,早期诊断和治疗非常重要,行膀胱全切术效果较确实,术后结合免疫疗法可延长生存时间。

Objective：To study the pathogenesis,diagnosis and treatment of squamous cell carcinoma of bladder.Methods：Clinical data of 8 cases of squamous cell carcinoma of bladder were analyzed retrospectively,related literature were reviewed.Results：Two patients underwent partial cystectomy,6 patients underwent radical cystectomy.All of 8 patients underwent post-operative radiotherapy or immunotherapy.1 patient who underwent partial cystectomy and received immunotherapy after operation is still alive by now.Among 6 patients who underwent radical cystectomy,2 patients are still alive,3 patients died because of metastasis,1 patient missed follow-up.Conclusion：The prognosis of squamous cell carcinoma of bladder is relatively poor;most of the patients were in advanced stage when diagnosed.The squamous cell carcinoma of bladder is highly malignant.It is very important for the patients to be early-diagnosed and early-treated.Radical cystectomy is by now the optimal treatment,immunotherapy can prolong the survival time.