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类风湿关节炎超微超顺磁性氧化铁颗粒增强MRI研究进展

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摘要 类风湿性关节炎(rheumatoid arthritis,RA)是一种常见而多发的以关节组织慢性炎症为主要表现的全身性疾病。如果得不到早期诊断与治疗,病情进展迅速,最终将导致关节强直、畸形和功能丧失。长期以来人们一直期望能找到早期诊断RA的方法,关于超微超顺磁性氧化铁(uhrasmall superparamagnetic ironoxide,USPIO)增强MRI是否能用于RA的早期诊断,笔者对近年来在RA发病机制、USPIO的理化特性、摄入机制和USPIO增强MRI用于RA的动物试验研究进展作了简要综述。
出处 《中华放射学杂志》 CAS CSCD 北大核心 2007年第12期1419-1420,共2页 Chinese Journal of Radiology
基金 安徽省高校自然科学基金(2006KJ305B) 安徽省重点科研项目基金(7020303072)
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