雏鸡人工感染鸡败血霉形体的研究

Studies on Chicken Experimentally Inoculated with Mycoplasma gallisepticum

半月龄SPF雏鸡人工感染鸡败血霉形体KPF21株后，试验鸡呈现血清学反应阳性并伴有较明显的临床症状；病理组织学变化以气管、气囊和肺内上皮细胞发生变性、坏死、脱落及组织内淋巴细胞和单核细胞浸润为特征，此外，心、肝、脾、肾等实质器官也发生不同程度的损伤。由于呼吸器官的损伤，呼吸功能障碍，试验鸡表现出慢性呼吸道症状。

Fifteen-old-SPF chickens were experimentally inoculated with Mycoplasma gallisepticumKPF21 .The results showed that chickens inoculated with MG appeared obvious clinical symptoms andpathomorphology. The changes of histopathology mainly appeared in air-pocket, trachea and lung. It wasfound that epithelium mucosae of trachea, air-pocket and lung showed degeneration, necrosis and losspartly. Lymphocyte and mononuclear cell infiltration was found also in tissue. Moreover, the liver,heart, spleen and kidney showed various degree of pathologic changes, and because of damage, the function of respiratory organs failed and even collapsed. The chickens inoculated with MG behaved in themanner of chronic respiratory disease.