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罗哌卡因与布比卡因用于蛛网膜下腔阻滞比较

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摘要 目的:探讨Rop用于蛛网膜下腔阻滞的有效性和安全性。方法:60例ASAⅠ~Ⅱ级行下腹部以下择期手术病人,男38例,女22例,年龄18~65岁,体重45~75kg,随机分为Rop组与Bup组,采用25G脊液穿刺针,于L3~4或L2~3进行蛛网膜穿刺,脑脊液流出后按双盲法注药。Rop组:1%Rop 1.5ml+10%GS 1ml;BUP组:0.75%BUP 1.6ml+10%GS 0.9ml,均不加肾上腺素。结果:两组是无统计学差异,ROP起效与达到完全阻滞的峰值时间较BUP长,持续时间较BUP短(P〈0.05)。R镇痛效果与肌松程度两组无显著性差异(P〉0.05),ROP组出现的心动过速,低血压较BUP组少(P〈0.01),其它不良反应的发生相近似。结论:ROP可以安全有效地用于蛛网膜下腔阻滞,尤其是对下腹部以下手术。
作者 张伟
出处 《内蒙古医学杂志》 2007年第10期1247-1248,共2页 Inner Mongolia Medical Journal
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