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1,3-丁二烯生物标志物的研究进展 被引量：5

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摘要 人类致癌物1,3-丁二烯对职业接触者的健康构成了严重的威胁,其生物标志物常被用来监测接触水平、评价损伤效应及预测可能的作用机制。寻找1,3-丁二烯的特异性生物标志物,有助于揭示1,3-丁二烯暴露与肿瘤发生过程中的重要生物学事件,提高危险度评价的精度。本文回顾了1,3-丁二烯3种生物标志物近期的研究进展,以期为更好地保护职业接触者提供技术依据。
作者 刘楠 程娟 李斌 王学生
机构地区 华北煤炭医学院 中国疾病预防控制中心职业卫生与中毒控制所
出处 《国外医学（卫生学分册）》 2007年第6期352-357,共6页 Foreign Medical Sciences(Section of Hygiene)
基金 国家自然科学基金(30471471)
关键词 l 3-丁二烯 生物标志物
分类号 R114 [医药卫生—卫生毒理学] R135.1 [医药卫生—劳动卫生]
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参考文献33

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同被引文献66

  • 1王伟华,韩占江.新疆慕萨莱思酒天然活性成分的代谢组学研究进展——以原花青素为例[J].食品安全质量检测学报,2013,4(6):1810-1814. 被引量：7
  • 2云水英,孙金秀,李斌.职业人群遗传多态性与1,3-丁二烯致癌作用的关系[J].国外医学（卫生学分册）,2006,33(5):305-310. 被引量：1
  • 3边洪英,李斌.1,3-丁二烯遗传学损伤与修复酶基因多态性的研究进展[J].国外医学（卫生学分册）,2006,33(6):325-329. 被引量：2
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  • 5Penn A, Snyder C A. 1,3-Butadiene exposure and cardiovascular disease[J]. Mutat Res, 2007, 621(1-2): 42-49.
  • 6Liu S, Ao L, Du B, et al. HPRT mutations in lymphocytes from 1,3- butadiene-exposed workers in China [J]. Environ Health Perspeet, 2008, 116(2): 203-208.
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  • 9Albertini R J, Sram R J, Vacek P M, et al. Molecular epidemiological studies in 1,3-butadiene exposed czech workers: female-male comparisons[J]. Chem Biol Interact, 2007, 166(1-3):63-77.
  • 10Georgieva N I, Boysen G, Upton P B, et al. Quantitative analysis of N-terminal valine peptide adduets specific for 1,2-epoxy-3-butene [J]. Chem Biol Interact, 2007, 166(1-3): 219-225.

引证文献5

二级引证文献8

国外医学（卫生学分册）
2007年 第6期

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