原位肝移植术后细菌感染的防治策略

Strategy of Prevent and Treat Bacterial Infection Occurred after Orthotopic Liver Transplantation

分析79例原位肝移植的临床资料,对感染部位、常见致病菌、导致细菌感染的危险因素进行分析。全组32例发生细菌感染,感染部位以肺部、腹腔多见。恢复饮食时间延长,术前肝功能C级、低蛋白血症、高血糖是感染的危险因素,肠道去污治疗是保护性因素。结论是尽可能的减少各种危险因素,有效的预防及早期确诊和治疗是防治细菌感染的关键。

The incidence and sites of postoperative bacterial infections as well as species in 79 patients underwent orthotopic liver transplantation（OLT） were analyzed retrospectively. Bacterial infections developed in 32 patients. The most common sites of infections were lung, abdominal cavity. The main risk factors include delayed restoration of gastrointestinal function, the liver function level C, hypoproteinemia and persistent postoperative hyperglycemia. Perioperative decontamination of the digestive tract had a protective effect. Therefore, removing the risk factors, early diagnosis and treatment of the infection are very important.