2-甲氧亚胺-2-(5-氨基-1,2,4-噻唑-3-基)乙酸苯并噻唑硫酯的合成工艺研究

The synthesis of 2-(5-amino-1,2,4-thiadiazol3-yl)-2-methoxy iminoacetic acid S-benzthiazolyl thioester

提供一条新的合成2-甲氧亚胺-2-(5-氨基-1,2,4-噻唑-3-基)乙酸苯并噻唑硫酯的工艺路线,以氰乙酸乙酯为原料,经过8步反应得到目标化合物,各步反应工艺简单,操作方便,原料易得,收率较高,成本较低,适合生产要求.

A new process for synthesizing 2 - （ 5 - amino - 1,2,4 - thiadiazol - 3 - yl ） - 2 - methoxy iminoacetic acid S -benzthiazolyl thioester is provided in this paper, ethyl cyanocaetate takes for raw material in this artical. After through eight - steps reaction, the product is obtained, each step of the technics is simple, easy to operation, the raw material is easy obtained, increasing the yield of the product, reducing the production costs greatly and being more helpful for the industrial production.