羊膜移植治疗蚕蚀性角膜溃疡

Amniotic membrane transplantation for chronic serpigionous corneal ulcer

目的评价羊膜移植对蚕蚀性角膜溃疡的治疗效果。方法临床上6例蚕蚀性角膜溃疡患者,年龄68～78岁,男5例,女1例,分别对其溃疡面及其相应球结膜组织及部分坏死巩膜组织进行切除并施行新鲜的羊膜移植手术。结果6例蚕蚀性角膜溃疡患者中,术后6例中4例术后当天疼痛消失,2例3天后消失。所有病人的视力均提高,2～3周后羊膜移植片溶解,溃疡面愈合。3～6个月随访无一例复发。结论新鲜羊膜移植对蚕蚀性角膜溃疡具有明显治疗效果。

Objective To investigate the effect of treatment that amniotic membrane transplantation on chronic serpigionous corneal ulcer. Methods The 6 patients diagnosed with chronic serpigionous corneal ulcer in clinical. 68-78 ages,including 5 men and 1 woman. We had section Keratoconjunctional focus and transplanted human amniotic membrane. Results Pain disappeared in 4 eyes in the day of operation and rehappened in 2 eyes three days later. Visual action improved in all patients. Amniotic membrane was melted 2-3 weeks after thd operation. Corneal ulcer recovers. All patients who were followed up for 3-6 months had no recurred. Conclusions The amniotic membrane transplantation is reasonable and effective to chronic serpigionous corneal ulcer.