磁共振功能成像鉴别胰腺癌与肿块型慢性胰腺炎的价值

Differentiation of Chronic Mass-Forming Type Pancreatitis from Pancreatic Carcinoma by Functional Magnetic Resonance Imaging

目的总结各种磁共振(MR)功能成像的原理及在胰腺癌及肿块型慢性胰腺炎诊断中的应用价值。方法回顾分析国内、外近年来关于MR波谱成像、MR弥散成像及MR灌注成像在胰腺癌及慢性胰腺炎诊断和鉴别诊断中应用的文献。结果胰腺癌与慢性胰腺炎在分子扩散、生化代谢、组织灌注等方面存在差异,MR功能成像方法能反映这些差异而用于鉴别诊断。结论MR功能成像作为一种非侵入性的影像检查方法,能够提供鉴别胰腺癌与肿块型慢性胰腺炎有价值的信息。

Objective To summarize the principle and application of functional MR imaging of pancreatic carcinoma and chronic mass-forming type pancreatitis. Methods Articles about diffusion-weighted imaging （DWI）, magnetic resonance spectrum imaging （MRSI） and dynamic contrast-enhanced MR imaging of pancreatic carcinoma and chronic pancreatitis were reviewed and analyzed. Results Functional MR imaging could reflected the differences in molecules diffusion, metabolism and tissue perfusion between pancreatic carcinoma and chronic pancreatitis. Conclasion As a non-invasive protocol, functional MR imaging can provide useful information in differential diagnosis between chronic mass-forming type pancreatitis and pancreatic carcinoma.