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肝移植围手术期HBV再感染的预防

Prevention of HBV Reinfection in Perioperative Period of Liver Transplantation
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摘要 目的探讨乙型肝炎病毒(HBV)相关疾病患者肝移植围手术期HBV再感染的预防措施。方法回顾近年相关文献并进行综述。结果对患HBV相关的急、慢性肝病的肝移植患者,预防移植后HBV再感染至关重要。目前不仅有多种预防HBV再感染的药物应用于临床,而且针对患者不同特点,在预防方案方面也有新的研究进展。结论肝移植是治疗HBV相关疾病的有效方法,围手术期合理准确地选择预防HBV再感染方案对延长患者肝移植术后存活期有重要意义。 Objective To investigate the prevention of HBV reinfection in the perioperative period of liver transplantation on HBV-related diseases. Methods Published papers were collected and reviewed. Results HBV- related diseases were the main indications of liver transplantation. The prevention for HBV reinfection affects the survivals remarkably. Nowadays, a lot of medication have been used in the prevention of HBV reinfection, and the therapeutic regimens were different from each other. Conclusion Liver transplantation is an effective treatment for HBV-related disease. Appropriate prevention of HBV reinfection in the perioperative period of liver transplantation is important for the survivals of patients.
作者 张宁 窦科峰
出处 《中国普外基础与临床杂志》 CAS 2007年第6期735-738,共4页 Chinese Journal of Bases and Clinics In General Surgery
关键词 肝移植 乙型肝炎病毒 乙肝免疫球蛋白 拉米夫定 阿德福韦 Liver transplantation Hepatitis B virus Hepatitis B immune globulin Lamivudine Adefovir
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参考文献32

  • 1Steinmuller T, Seehofer D, Rayes N, et al. Increasing applicability of liver transplantation for patients with hepatitis B-relat ed liver disease[J]. Hepatology, 2002; 35(6): 1528
  • 2Yao FY, Terrault NA, Freise C, et al. Lamivudine treatment is beneficial in patients with severely decompensated cirrhosis and actively replicating hepatitis B infection awaiting liver trans plantation: a comparative study using a matched, untreated cohort[J]. Hepatology, 2001; 34(2):411
  • 3Perrillo RP, Wright T, Rakela J, et al. A multicenter United States-Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B[J].Hepatology, 2001,33(2):424
  • 4Villeneuve JP, Condreay LD, Willems B, et al. Lamivudine treatment for decompensated cirrhosis resulting from chronic hepatitis B[J]. Hepatology, 2000; 31(1) :207
  • 5Lo CM, Cheung ST, Lai CL, et al. Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis[J]. Ann Surg, 2001; 233(2):276
  • 6Perillo RP. Potential importance of the sexual transmission of non-A, non-B hepatitis[J]. Hepatology, 1991, 13(4):805
  • 7Fontana RJ, Hann HW, Perrillo RP, et al. Determinants of early mortality in patients with decompensated chronic hepatitis B treated with antiviral therapy [J]. Gastroenterology, 2002; 123(3) : 719
  • 8Peters MG, Hann Hw H, Martin P, et al. Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B[J].Gastroenterology, 2004,126(1):91
  • 9Schiff ER, Lai CL, Hadziyannis S, et al. Adefovir dipivoxi therapy for lamivodine-resistant hepatitis B in pre-and post liver transplantation patients [J]. Hepatology, 2003; 38 (6):1419
  • 10Villeneuve JP, Durantel D, Durantel S, et al. Selection of a hepatitis B virus strain resistant to adevir in a liver transplantation patient[J]. J Hepalo, 2003, 39(6):1085

二级参考文献14

  • 1Todo S, Demetris A, Van Thiel D, et al. Orthotopic liver transplantation for patients with hepatitis B virus-related liver disease [J]. Hepatology, 1991,13(4) : 619
  • 2Steinmuller T, Seehofer D, Rayes N, et al. Increasing applicability of liver transplantation for patients with hepatitis B-related liver disease [J]. Hepatology, 2002; 35(6) : 1528
  • 3Ben-Ari Z, Shmueli D, Mor E, et al. Beneficial effect of lamivudine treatment of advanced and decompensated liver disease due to hepatitis B [J]. Hepatogastroenterology, 1997,44(15) : 808
  • 4Nery JR, Weppler D, Rodiriguez M, et al. Efficacy of lamivudine in controlling hepatitis B virus recurrence after liver transplantation [J]. Transplant Proc, 1997,29(6) : 2687
  • 5Lo CM, Fung JT, Lau GK, et al. Development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B[J]. Hepatology, 2003, 37(1): 36
  • 6Maruyama T, Mitsui H, Hanajiri K, et al. Anti-HBs antibodies produced after liver transplantation: from the donor or the recipient? [J]. Hepatology, 2003; 38(1) : 271
  • 7Seehofer D, Rays N, Steinmuller T, et al. Viral load at the time of liver transplantation and risk of hepatitis B virus recurrence [J]. Liver Transpl, 2005,11(4) : 402
  • 8Steinberg JL, Yeo W, Zhong S, et al. Hepatitis B virus reactivation in patients undergoing cytotoxic chemotherapy for solid tumours: precore/core mutations may play an important role[J]. J Med Virol, 2000; 60(3): 249
  • 9Akay S, Karasu Z, Akyildiz M, et al. Adefovir treatment in posttransplant hepatitis B virus infection resistant to lamivudine plus hepatitis B virus immunoglobulin [J]. Transplant Proc,2004; 36(9):2768
  • 10Angus P, Vaughan R, Xiong S, et al. Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase [J]. Gastroenterology, 2003; 125(1):292

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