膀胱小细胞癌的诊治——附二例报告

Small cell carcinoma of the bladder:a report of 2 cases

为了探讨膀胱小细胞癌的诊断及治疗方法,对2例膀胱小细胞癌临床资料、治疗方法及随访结果进行了总结分析。病例1术后病理示膀胱小细胞癌,随访8个月后因全身多器官功能衰竭死亡。病例2术后病理示膀胱低分化癌伴神经内分泌癌。根治性手术后GC方案化疗6个疗程,随访中。初步观察结果提示,膀胱小细胞癌尽管比较少见,但因其恶性程度高,更具侵袭性,转移的更早、更快,应该引起重视,根治性手术治疗辅以系统的化疗将有助于提高生存率和延长生存时间。

The objective of this study was to discuss the diagnosis and therapy of small cell carcinoma of the bladder. The clinical data, therapy methods and prognosis of 2 small cell carcinoma cases were analysed. The pathological result of case 1 was small cell carcinoma, which was died of multiple organ failure after following-up for 8 months. The case 2 accepted 6 times GC plan chemotherapy after radical eysteetomy and survive at present. The pathological result was poorly differentiated carcinoma of bladder with neuroendoerine carcinoma. In conclusion, although small cell carcinoma of bladder was a rare tumor, it has some special characteristics such as high-degree malignant, aggressive behavior, early metastatsis and so on. The patients＇ survival time can be prolonged by the radical eysteetomy in combination with systemic chemotherapy.