摘要
到目前为止,氨基水杨酸类制剂、肾上腺糖皮质激素和免疫抑制剂治疗克罗恩病(CD)的有效性和安全性均有局限。CD仍是难以治愈的疾病。随着对CD治疗新靶点的发现,生物药物治疗成为研究的方向,人类可能停止或减少依赖非特异性的免疫抑制药物。本文概述目前探索用于针对肿瘤坏死因子、干扰素、细胞因子等靶点治疗CD的一些生物药物。
So far,the effectiveness and safety of the aminosalicylic acid preparations,glucocorticoid and immunosuppressants have limitation on Crohn＇s disease（CD）.It is still difficult to cure CD.Along with the discovery of new targets in CD treatment,biological pharmacotherapy become a direction of study.People may stop or reduce the dependence on non-specific immunosuppressive drugs.Some biological drugs that are currently explored for therapy CD targeting at tumor necrosis factors,interferons,cytokines and so on are summarized.
出处
《现代诊断与治疗》
CAS
2007年第6期356-360,共5页
Modern Diagnosis and Treatment
