深圳市无偿献血者输血相关传染病标志物检测结果分析

Analysis of five transfusion transmitted diseases sero-marks detection results in Shenzhen blood donors

目的了解深圳市无偿献血者输血相关传染病标志物检测结果,为安全输血招募低危无偿献血者提供科学的理论依据。方法采用回顾性调查方法,对2000～2005年深圳市无偿献血检测结果进行统计分析。结果共计检测268737人份,总不合格率为4.41%,呈逐年显著下降趋势(χ2=527,P<0.001),其中抗-HCV阳性率和抗-HIV确证阳性率呈稳定态势(χ2=0.88,P>0.05及χ2=24.1,P>0.05),抗-TP阳性率呈逐年增加趋势(χ2=25.1,P<0.001),ALT异常率和HBsAg阳性率呈逐年下降趋势(χ2=1033,P<0.001及χ2=26.6,P<0.001)。结论有必要提高检测方法准确度,加强招募前教育和筛查,进一步提高输血安全。

[Objectives] To investigate the infection rate of five transfusion transmitted diseases sew-marks in the blood donors in shenzhen city, and to provide scientific basis for blood transfusion safety and the recruitment of low risk blood donors. [Methods] Analyzed the detection results of blood screening in shenzhen from 2000 to 2005 with retrospective investigation method. [Results] 268737 samples were detected in six years, the positive rate was 4.41% and there was a significant decline tendency （X^2=527, P〈0.001）, The positive rate of anti-HCV and anti- H1V were stable（x^2=0.88, P〉0.05 ＆ X^2=24.1, P 〉0.05）, and anti-TP＇s increased significantly （x^2=25.1, P 〈0.001）. Both of the abnormal rate of ALT and positive rate of HBsAg decreased significantly（x^2=1033, P 〈0.001＆ x^2=26.6, P 〈0.001 ）. [ Conclusions] It is necessary to improve the accuracy of detection methods for blood screenings and lightened up the education of blood donor and enhanced Dre-tests before donation.