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消异止痛煎对兔子宫内膜异位症模型的实验研究 被引量:4

Lab Study of Xiaoyizhitong Decoction on Model Rabbit of Endometriosis
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摘要 目的:探讨消异止痛煎对子宫内膜异位症的治疗作用。方法:采用兔子宫内膜自身种植法制作实验性兔子宫内膜异位症模型。将模型兔分为三组:中药组、西药组、模型组。中药组予消异止痛煎剂,西药组予丹哪唑,两组均灌胃给药,模型组不做特殊处理。观察各组大体解剖情况、组织学改变、血浆、血清水平等。结果:中药组和西药组的大体解剖结果、组织学改变情况明量优于对照组(P<0.01);血浆PGF2α、FGE2两用药组均优于模型组(P<0.05,P<0.01);血清FSH、LH、E2水平,两用药组明显优于对照组(P<0.01),PRL水平各组均有明显上升,但无显著性差异(P>0.05)。结论:消异止痛煎能降低兔子宫内膜异位症前列腺素水平,缓解痛经症状。 Objective: To investigate the effect of Xiaoyizhitong Decoction on Model Rabbit of Endometriosis. Methods: the rabbits was divided into 3 groups randomly. Xiaoyizhitong Decoction was given to therapeutic group by Chinese medicine and dannazuo was given to therapeutic group by westen medicine. The information of gross anatomy and change of histology were observed , PGF2αand FGE2 of blood plasma, FSH, LH and Ee of serum were examined. Results: Gross anatomy and change of histology were superior to that of control group(P〈0.01). PGF2αand FGE2 of blood plasma were superior to that of control group( P 〈 0.05, P〈0.01 ). And FSH, LH and E2 of serum were superior to that of model group ( P〈 0.01). There is no difference between PRL of 2 groups.
出处 《世界中西医结合杂志》 2007年第1期14-17,共4页 World Journal of Integrated Traditional and Western Medicine
关键词 消异止痛煎剂 子宫内膜异位症 前列腺素 激素水平 毒理作用 Xiaoyizhitong Decoction Endometriosis Prostaglandin Hormone level Toxic effect
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