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The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers

The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers
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摘要 The positively charged single walled carbon nanotubes (SWNTs^+) were prepared by conjugating with -CONH-C6H12-NH3^+. The double strand DNA (dsDNA) chains were loaded onto SWNTs^+ via the electrostatic interactions. SWNTs^+ shows improved loading efficiency (353.5 μg/mg) toward dsDNA compared with that of charged free single walled carbon nanotubes (SWNTs) (82.9 μg/mg). The positively charged single walled carbon nanotubes (SWNTs^+) were prepared by conjugating with -CONH-C6H12-NH3^+. The double strand DNA (dsDNA) chains were loaded onto SWNTs^+ via the electrostatic interactions. SWNTs^+ shows improved loading efficiency (353.5 μg/mg) toward dsDNA compared with that of charged free single walled carbon nanotubes (SWNTs) (82.9 μg/mg).
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2007年第12期1551-1553,共3页 中国化学快报(英文版)
关键词 Single wailed carbon nanotubes DNA Carder Single wailed carbon nanotubes DNA Carder
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  • 1Li Ping Wang~1 Ke Liang~2 Yu Shen~2 Wei Bo Yin~2 G.Hans~3 Yan Jun Zeng~1 ~1Biomechanics & Medical Information Institute,Beijing Polytechnic University,Beijng 100022,China ~2Department of Gastrointestinal Surgery,Aalborg University,Denmark ~3Cancer Institute (Hospital),Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100021,ChinaLi Ping Wang graduated from Beijing Polytechnic University in 2000,major in tumor radiotherapy,having 3 papers published..Neutron-induced apoptosis of HR8348 cells in vitro[J].World Journal of Gastroenterology,2001,7(3):435-439. 被引量:5

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