视诱发电位在中药治疗萎缩型年龄相关性黄斑变性中的应用

The Application of Visual Evoked Potential in Traditional Chinese Medicine Treating Atrophic Age-Related Macular Degeneration

目的:利用现代化的视诱发电位检测方法来观察中药治疗年龄相关性黄斑变性萎缩型的疗效。方法:治疗组30例年龄相关性黄斑变性萎缩型患者给于滋补肝肾、利水渗湿、软坚散结为主要组方的中药治疗2个月,对照组25例年龄相关性黄斑变性萎缩型患者用维生素治疗2个月,所有病例在治疗前后进行图形P-VEP的检查,观察P-VEP的改变。结果:治疗组治疗前后P-VEP的振幅改变有显著性差异(P<0.05),对照组无差异(P>0.05)。结论:视诱发电位技术可以应用于中药治疗年龄相关性黄斑变性萎缩型的疗效观察。

Objective： To observe the therapeutic efficacy of traditional Chinese medicine treating atrophic age -related macular degeneration（AMD） by visual evoked potential （VEP）. Methods ： In the treatment group, 30 cases （ 35eyes ） with atrophic AMD had been treated by traditional Chinese medicine for two months. In the control group, 25 cases （29eyes）with atrophic AMD had been treated by vitamin C,E for two months. All patients had been examined by P- VEP before and after therapy. Results ： There was statistical difference in the amplitude of P - VEP before and after treatment in the treatment group （ P 〈 0.05）. Conclusion： Visual evoked potential should been appliced to observe the therapeutic effect of traditional Chinese medicine curing atrophic AMD.