妇科消炎栓的药效作用与临床疗效观察

Gynopathic antiphlogistic suppository: pharmacodynamics research and clinical effect

目的：探讨妇科消炎栓（中药制剂）治疗宫颈炎的药效作用及临床疗效。方法：①抗炎：以二甲苯涂抹于鼠耳致炎，用肉芽肿形成法，观察药物的抗炎作用。②收敛：以体外蛋白沉淀法，对离体肠粘膜、皮肤的直接作用观察药物的收敛作用。③抗菌：采用平皿法与试管法，体内注射大肠杆菌、绿脓杆菌皮肤感染进行体外、体内抗菌实验。④临床：对２１０例宫颈炎患者用本品进行治疗观察。结果：本品有抗急性炎症、收敛及体外抑菌作用。临床治疗宫颈炎，总有效率９８．６％，未见明显不良反应。结论：本品对湿热下注及血瘀带下型宫颈炎疗效显著，使用方便，无刺激。

OBJECTIVE: To explore the pharmacological effects and clinical efficacy of gynopathic antiphlogistic suppository (GAS, preparation of Chinese materia medica) in the treatment of cervicitis. METHOSDS: Antiinflammatory function: Xylol was spread on the mouse ears to induce inflammation. The method of granuloma formation was used to observe the anti inflammatory function of the drug. Astringency: The drug astringency function on the bowel mucosa and skin was observed with the method of exosomatic protein precipitation. Antibioses: Extrasomatic and intracorporeal antibiotic experiment with the plate and test tube method was used. Clinical: 210 patients undergoing cervicitis, were observed. RESULTS: GAS can eliminate acute inflammation, and has astringency and extrasomatic antibiotic function. Its total efficiency rate was 98.6%. CONCLUSION: GAS has evident effect on cervicitis.