幽门螺杆菌感染与老年人胃癌的相关性分析

Analyzing the Related Factors of Hp Infection with Gastric Carcinoma of the Ageol

目的:研究幽门螺杆菌(HP)感染与老年人胃癌的相关性。方法:分别对40名老年胃癌患者和40名胃镜检查为慢性胃炎的老年病人进行HP检测,检测方法采用13C-尿素呼气试验(13C-UBT)、胃粘膜组织涂片、Gram染色、病理组织切片、HE染色分析。结果:胃癌组HP阳性率高于对照组(P<0.05)。早期胃癌HP感染率高于进展期(P<0.05);肠型胃癌HP感染率明显高于弥漫型及混合型胃癌(P<0.01);非贲门部胃癌HP感染率高于贲门部胃癌(P<0.05)。结论:老年人胃癌的发生与HP感染有密切关系。

Objective： To study the dependablity of Helicobacter pylori.（Hp） infection and gastric carcinoma of the aged.Method： For 40 aged patients with gastric carcinoma and 40 aged patients diagnosed chronic gastritis by gastroscopy,Helicobacter pylori.were detected by 13C-urea breath test（13C-UBT）,gastric mucosa smear,gram positive stainning,histopathologic slide and HE staining,respectively.Result： Hp positive ratio of gastric carcinoma group was prominently higher that of control group（p〈0.05）.Hp infection ratio in early gastric cancer was higher than that of progression（p〈0.05）;in intestine-type gastric carcinoma was much higher than that in suffusion-type and mixed type gastric carcinoma（p〈0.05）;and in gastric carcinoma of non-pars cardiaca.was higher than in that of pars cardiaca.Conclusion： The development of gastric carcinoma of the aged was closely relative with Hp infection.