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^(99m)Tc-MIBI显像及定量分析定位诊断甲状旁腺腺瘤的临床应用 被引量:3

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摘要 目的根据高功能甲状旁腺对MIBI摄取增高的原理,应用SPECT和平面显像定量分析评价术前定位原发性甲旁亢的诊断价值。方法对21例原发性甲旁亢患者采用99mTc-MIBI平面双时相显像及定量分析作术前定位;其中4例加作SPECT断层显像。检测所有病人血清PTH水平及血清钙水平。定量分析采用靶甲状旁腺腺瘤与最大甲状腺放射性(ROI)平均计数比率和靶甲状旁腺腺瘤(T)与对侧相应甲状腺(NT)比值计算。结果双时相平面显像的敏感性为81%(17/21);其中4例平面显像假阴性者2例经SPECT断层获得阳性定位(1例异位腺瘤、1例腺瘤虽然位置正常但同时存在多发结节性甲状腺肿);另2例假阴性者为位置正常但摄取99mTc-M IB I低的腺瘤。甲状旁腺腺瘤对最大甲状腺放射性计数的平均摄取比值和T/NT比值分别为0.95±0.41和2.51±1.76。结论99mTc-MIBI显像是最有效的探测甲状旁腺腺瘤的方法;对探测异位性甲状旁腺腺瘤或同时存在多发结节性甲状腺肿时SPECT断层的敏感性比平面显像更高。
出处 《中国辐射卫生》 北大核心 2007年第4期477-479,共3页 Chinese Journal of Radiological Health
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参考文献13

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同被引文献31

  • 1周建平,李晓莉,董明,郭克建,田雨霖.我国原发性甲状旁腺功能亢进症的误诊情况分析[J].中国现代医学杂志,2006,16(7):1040-1042. 被引量:50
  • 2魏晓峰,杜涛,周菊.甲状旁腺功能亢进症^(99m)Tc-MIBI核素显像14例分析[J].中国误诊学杂志,2007,7(6):1320-1320. 被引量:2
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