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钴疗机分次高剂量适形放疗中晚期肺癌的临床观察

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摘要 目的观察钴疗机分次高剂量适形放射治疗中晚期肺癌的疗效。方法共收集2002年8月至2005年6月我科用钴疗机做适形放疗的59例中晚期肺癌病例。其中,首次放疗51例,术后或放疗后复发8例,男性52例,女性7例;年龄31岁~85岁,中位年龄70岁;卡氏评分均≥70分。按1997年UICC临床分期;临床Ⅱ期11例,Ⅲ期42例;Ⅳ期5例.病理类型:鳞癌32例,腺癌6例,未分化癌8例,鳞腺癌3例,影像诊断10例。周围型15例,中央型44例。瘤体最大径≤5cm;10例,〉5cm〈8cm;34例,≥8cm;15例。瘤体直径最小为2.4cm,最大为12.8cm。用80%等剂量线覆盖GTV的靶区范围,肿瘤边缘剂量4~5Gy/次,5次/周,13~15次/2.5~3.5周。结果1、2a总生存率为45.8%、20.3%。目前生存10人,死亡49人,其中局部复发20人,远处转移27人,死于冠心病3人。结论临床实践显示肿瘤适形放疗疗效优于普通放疗。
出处 《中国辐射卫生》 北大核心 2007年第4期486-487,共2页 Chinese Journal of Radiological Health
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