期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Fas/FasL在缺血-再灌注心肌细胞凋亡中的作用研究进展

下载PDF
导出
摘要 在动物实验和临床观察中发现,恢复缺血组织的血液再灌注后,部分动物或患者细胞功能代谢障碍及结果破坏反而加重,人们把这种血液再灌注后缺血性损伤进一步加重的现象称为缺血-再灌注损伤（ischemia-reperfusion injury）。缺血-再灌注损伤是在缺血性损伤基础上发展而来的,再灌注可以使可逆性缺血损伤加重,亦可能促进可逆性缺血损伤转化为不可逆性损伤。
作者 左汉恒 黄绍烈
机构地区 南昌大学第一附属医院
出处 《实用中西医结合临床》 2007年第6期91-92,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词 FAS/FASL 缺血-再灌注损伤 心肌 细胞凋亡 综述
分类号 R965 [医药卫生—药理学]
  • 相关文献

参考文献2

二级参考文献36

  • 1KaiSun,Zhi-SuLiu,QuanSun.Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning[J].World Journal of Gastroenterology,2004,10(13):1934-1938. 被引量：86
  • 2Heather HARTIG,Ivan DZHAGALOV,David DRAPER.The role of apoptosis in the development and function of T lymphocytes[J].Cell Research,2005,15(10):749-769. 被引量：16
  • 3Zender L,Hutker S,Liedtke C,et al.Caspase 8 small interfering RNA prevents acute liver failure in mice. Proceedings of the National Academy of Sciences of the United States of America . 2003
  • 4Rodriguez I,Matsuura K,Khatib K,et al.A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection. The Journal of Experimental Medicine . 1996
  • 5Arjang Djamali,Kenneth R. Waller,Jonathan McAnulty,Debra Hullett,Bryan N. Becker,Jon S. Odorico.Intrathymic injection of anti-Fas monoclonal antibody prolongs murine non-vascularized cardiac allograft survival[J]. Transplant International . 2004 (6)
  • 6W ang X,DeFrances MC,Dai Y,Pediaditakis P,Johnson C,Bell A, et al.A mechanism of cell survival: sequestration of Fas by the HGF receptor Met. Molecular Cell . 2002
  • 7Z ucchini N,,de Sousa G,Bailly-Maitre B,Gugenheim J,Bars R,Lemaire G, et al.Regulation of Bcl-2 and Bcl-xL anti- apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes. Biochimica et Biophysica Acta . 2005
  • 8S utton VR,Vaux DL,Trapani JA.Bcl-2 prevents apoptosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes. J Immunol . 1997
  • 9Rao JN,Guo X,Liu L,Zou T,Murthy KS,Yuan JX, et al.Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution. American Journal of Physiology Cell Physiology . 2003
  • 10Z hang X,Brunner T,Carter L,Dutton RW,Rogers P,Bradley L, et al.Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/ FasL-mediated apoptosis. The Journal of Experimental Medicine . 1997

共引文献26

实用中西医结合临床
2007年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部