早期应用他汀治疗对血脂正常的急诊PCI患者短期预后的影响

Effects of Early Statins Treatment on In-hospital Prognosis in AMI Patients Successfully Revascularized by Emergency PCI

目的探讨对于血脂正常的急性心肌梗死患者行急诊PTCA术成功后,用或不用他汀类药物对住院期间病死率、左室射血分数及平均住院天数等短期预后的影响。方法急性心肌梗死行急诊PTCA术成功、血清TC与LDLC正常的患者共133例随机分为他汀组(83例)和对照组(69例),观察早期他汀治疗对急性心肌梗死行PCI术成功的患者的住院期间病死率、左室射血分数和住院天数的影响。结果与对照组相比,他汀组的住院病死率下降,左室射血分数增加,住院天数缩短。结论急性心肌梗死成功PCI后,早期他汀治疗可有效改善住院病死率、左室射血分数和住院天数等短期预后。

Objective To explore the effects of early statins treatment on in - hospital mortality, left ventricular ejection fraction and length of stay in acute myodardial infarction patients successfully revascularized by emergency percutaneous coronary intervention. Methods 133 acute myodardial infarction patients successfully revascularized by emergency percutaneous coronary intervention, whose total cholesterol and low density lipoprotein- cholesterol are normal, are randomly divided into two matched groups： atrovastatin group and control group. And beween the two groups, in - hospital mortality, left ventricular ejection fraction and length of stay were contrasted. Resuits Compared with control group, strovastatin group＇ s in - hospital mortality, left ventricular ejection fraction and length of stay were significantly lowered. Conclusion Early statins treatment can effectively promote inhospital mortality, left ventr/cular ejection fraction and length of stay in acute myodardial infarction patients successfully revascularized by emergency percutaneous coronary intervention.