3,4-二取代呋喃-2,5-二甲酸二甲酯的合成

Synthesis of dimethyl 3,4-disubstituted furan-2,5-dicarboxylates

以二甘醇酸二甲酯和1，2-二羰基化合物（二苯乙二酮、二水合三聚乙二醛或草酸二乙酯）为原料，甲醇为溶剂，在CH3ONa的作用下，回流6h，经一步反应合成了3个标题化合物，产率69．1％～97．4％。

Three dimethyl 3,4- disubstituted furan-2,5-dicarboxylates were synthesized in the yields of 69.1% - 97.4% using dimethyl diglycolate and 1,2-carbonyl compounds（benzil, glyoxal trimer dihydrate or diethyl oxalate） as raw materials after refluxing for 6 h in methanol in the presence of CH3ONa in one step.