鱼腥草滴眼液治疗新生儿泪囊炎100例临床观察

Clinical Observation of Houttuynia Cordate Thunb Eyedrops in Treatment for 100 Neonatal Patients with Dacryocystitis

目的观察鱼腥草滴眼液对新生儿泪囊炎的临床疗效和不良反应。方法将新生儿泪囊炎患儿随机分为治疗组和对照组,治疗组52例(65眼),予鱼腥草滴眼液滴眼,并以鱼腥草滴眼液作泪道冲洗和探通的冲洗液。对照组48例(50眼),予抗生素滴眼液滴眼,并以生理盐水作泪道冲洗和探通的冲洗液。结果治疗组和对照组经泪道加压冲洗和泪道探通术后,通过率为100%。术后随访6个月行泪道冲洗,治疗组仍保持通畅为60眼,占92.3%,对照组仍保持通畅为31眼,占62.0%,两组差异有显著统计学意义(P<0.01)。治疗组中未发现不良反应。结论应用鱼腥草滴眼液治疗新生儿泪囊炎疗效确切,安全可靠。

Objective To evaluate the efficacy and aftereffect of Houttuynia Cordate Thunb eyedrops on neonatal dacryocystitis.Methods The patients with neonatal dacryocystitis were divided randomly into trial group（52 patients,65 eyes） and control group（48 patients, 50 eyes）.Houttuynia Cordate Thunb eyedrops were administered in the trial group,and were used as irrigative liquor in the irrigation and probing of lacrimal passage.Antibiotic eyedrops were administered in the control group,and normal saline were applied as irrigative liquor in the irrigation and probing of lacrimal passage.Results All the patients（100%） of the two groups were cured after the pressure irrigation and probing of lacrimal passage.After six months＇postoperative follow-up,60 eyes of the trial group got smooth irrigation（92.3%）,while 31 eyes of the control groups got smooth irrigation（62.0%）.There was a significant difference between the two groups（P〈0.01）.There were not local and general side effects observed in the trial group.Conclusion Houttuynia Cordate Thunb eyedrop is a useful and safe medicament for neonatal dacryocystitis.