急性有机磷农药中毒合理使用抗胆碱药的疗效观察

Effects of the reasonable administration of the anticholine drugs on acute organophosphorus pesticides poisoning

目的探讨急性有机磷农药中毒的抗胆碱药合理应用。方法我们根据简化阿托品化指标和动态胆碱酯酶活力测定结果,及时调整长效托宁和阿托品的用量和时间,来治疗急性有机磷农药中毒。结果使用以上方法治愈急性有机磷农药中毒,抗胆碱药用药总量小,治愈时间短。结论抗胆碱药合理应用在急性有机磷农药中毒治疗中具有实用性价值,值得临床推广。

Objective：To study the reasonable administration of the anticholine drugs on acute organophosphorus pesticides poisoning.Methods：On the basis of simple-atropinization and cholinesterase activity,we adjusted the total administrative amount and time to treat the patients with acute organophosphorus pesticides poisoning in time.Fifty-seven cases of the patients were randomly divides into therapy and control groups treated with the long effective Tuoning and atropine respectively.Consequently the clinical effects were compared between two groups.Results： The total administrative amount and time of anticholine drugs were less by above mentioned methods.Conclusion：The reasonable administration of the anticholine drugs on acute organophosphorus pesticides poisoning is practical and worthy of generalization.