血清AFP、CEA联合检测诊断原发性肝癌临床研究

Clinical Study on Diagnosing Primary Hepatic Carcinoma by Alpha Fetoprotein and Carcino-embryonic Antigen

目的:探讨应用化学光标记免疫法联合检测血清甲胎蛋白(AFP)、癌胚抗原(CEA)对原发性肝癌的诊断价值。方法:以化学光标记免疫法对原发性肝癌组32例、肝硬化组22例、慢性肝炎组30例、正常对照组35例的AFP、CEA进行联合检测。结果:原发性肝癌组AFP阳性23例(71.88%)、CEA阳性89例(25.00%),阳性率明显高于肝硬化组和慢性肝炎组(P<0.05),同时应用AFP、CEA联合检测对原发性肝癌的诊断率可达90.63%。结论:AFP、CEA联合检测对于诊断原发性肝癌具有重要的意义。

Objective： To study the dignosing value of primary hepatic carcinoma by alpha fetoprotein （AFP） and carcino-embryonic antigen（CEA）. Methods： Chemoluminescence immunifaction was used to examine AFP and CEA on 32 cases of primary hepatic carcinoma, 22 cases of hepatic cirrhosis, 30 cases of chronic hepatitis and 35 normal contral persons. Results. AFP of 23 cases were positive in 32 cases of primary hepatic carcinoma. CEA of 8 cases were positive, The positive was higher than that of hepatic cirrhosis and chronic hepatitis. The diagnosis rate was amount to 90.63%. Conclusion： AFP and CEA could be used to diagnose primary hepatic carcinoma.