Measuring radial Young’s modulus of DNA by tapping mode AFM 被引量：1

Measuring radial Young’s modulus of DNA by tapping mode AFM

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摘要 Based on tapping mode AFM imaging, a method was demonstrated to evaluate compression elasticity of single double-stranded DNA (dsDNA) molecules in the force region. With images under ambient conditions, Young’s moduli of dsDNA in compression were calculated. Results demonstrated that Young’s moduli of dsDNA can be simply deduced according to the proposed model. The method can also be used to evaluate the compression elasticity of similar soft nanomaterials. Based on tapping mode AFM imaging, a method was demonstrated to evaluate compression elasticity of single double-stranded DNA （dsDNA） molecules in the force region. With images under ambient conditions, Young＇s moduli of dsDNA in compression were calculated. Results demonstrated that Young＇s moduli of dsDNA can be simply deduced according to the proposed model. The method can also be used to evaluate the compression elasticity of similar soft nanomaterials.

作者 LIN Yi SHEN XinCheng WANG JingJing BAO Lei ZHANG ZhiLing PANG DaiWen

机构地区 College of Chemistry and Molecular Sciences

出处《Chinese Science Bulletin》 SCIE EI CAS 2007年第23期3189-3192,共4页

基金 Supported by the National Key Scientific Program (Grant No. 2006CB933100) the Science Fund for Creative Research Groups of NSFC (Grant No. 20621502) China Postdoctoral Science Foundation (Grant No. 20060400867)

关键词测量光线抽头模型弹性显微镜 DNA, Young＇s modulus, elasticity, atomic force microscopy

分类号 O43 [机械工程—光学工程]

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