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脑星形细胞瘤影像表现与病理对照研究 被引量:3

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摘要 目的:分析不同级别脑星形细胞瘤的影像表现,探讨影像表现与脑星形细胞瘤病理分级的相关性。方法:收集经CT及MRI诊断和手术病理证实的脑星形细胞瘤85例,按病理诊断标准分为四级,Ⅰ级13例,Ⅱ级21例,Ⅲ级28例,Ⅳ级23例。对肿瘤大小、密度、水肿、钙化、强化程度、强化类型等CT表现与病理分级进行对照研究,采用卡方检验;对MRI表现的8个特征(信号不均匀性、囊变坏死、出血、越过中线、水肿、边界、强化程度及强化不均匀性)与星形细胞瘤病理分级进行统计分析,采用卡方检验。结果:(1)肿瘤的大小、钙化等情况在各组间差异无显著性(P>0.05);而肿瘤密度、瘤周水肿、强化程度及类型在各组间差异存在显著性(P<0.05)或高度显著性(P<0.01);(2)除越过中线外,其余7个MRI征象均对星形细胞瘤分级有较大的帮助,尤其是囊变坏死、边界、水肿、肿瘤强化程度及强化不均匀性在各级星形细胞瘤之间差异均有极显著性意义(P<0.01)。结论:星形细胞瘤影像表现与其病理分级有一定的相关性,CT及MRI对星形细胞瘤的分级诊断有较大的价值。
出处 《实用医学杂志》 CAS 2007年第23期3738-3740,共3页 The Journal of Practical Medicine
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  • 1吴仁华,郎志谨.颅内肿瘤脑水肿的CT与病理对照研究[J].中华放射学杂志,1993,27(7):454-457. 被引量:18
  • 2吴仁华,郎志谨,徐霞,袁江河,孙玉阳.单发脑转移瘤的CT与MRI特征[J].中国医学影像学杂志,1995,3(4):238-240. 被引量:5
  • 3[1]Kleihues P,Burger PC,Scheithauer BW. The new WHO classification of brain tumor[J]. Brain Pathol,1993,3:255~268.
  • 4[2]Weidner N, Folkman J, Pozza F,et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early stage breast carci noma[J]. J Natl Cancer Inst, 1992,84(24):1875~1887.
  • 5[3]Cao Y, Linden P, Farnebo J, et al. Vascular endothelial gro wth factor induces angiogenesis in vivo [J]. Proc Natl Acad Sci USA, 199 8,95(24):14389~14394.
  • 6[4]Leon SP,Folkerth RD,Black PM. Microvessel density is a prognost ic indicator for patients with astroglial brain tumors[J]. Cancer, 1996,77(2): 362~372.
  • 7[5]Tynninen O, Aronen HJ,Ruhala M, et al. MRI enhancement and microvascular density in gliomas correlation with tumor cell proliferation[J] . Invest Radiol, 1999,34(6):427~434.
  • 8沈海林,丁乙,陈学仁.MRI评分对星形细胞瘤病理分级的相关性研究[J].中国医学计算机成像杂志,1997,3(1):1-4. 被引量:7
  • 9沈海林,丁乙,陈学仁,胡春洪,付引弟,康苏娅.星形胶质细胞瘤的MRI与病理对照研究[J].临床医学影像杂志,1998,9(2):97-100. 被引量:4

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  • 1贾洪顺,梁文,孙涛.颅内少支-星形细胞瘤15例MRI表现[J].实用医学杂志,2006,22(3):306-307. 被引量:5
  • 2Kleihues P,Cavenee WK.World Health Organization classification of tumors of the nervous system[C].France:lntemational Society of Neu ropathology International Academy of Pathology and the Preuss Fouda-tion of Brain Tumor Research,1999.
  • 3Freb GB,Sucm ML,Stephen LH,et al.Age and the risk of anaplasia in MR nonenhancing supratentorial cerebral tumors[J].Cancer,1997,80(5):936-941.
  • 4Pierallini A,Bonamini M,Bozzao A,et al.Supratentorial diffuse as tro-cytic tumours:proposal of an MRI classification[J].Eur Radiol.1997,7(3):395-399.
  • 5Louis D N, Ohgaki H, Wiestler O D, et al. WHO Classification of tumours of the central nervous system [ M ]. Lyon: International Agency for Research on Cancer, 2007 : 8-11.
  • 6Grabb P A, Albright L A, Sclabassi R J, et al. Continuous intraoperative electromygraphic monitoring of cranial nerve duiring resection of fourth ventriclar tumors in children [J]. J Neurosurg, 1997,86 : 1-4.
  • 7Louis D,Ohgaki H,Wiestler O,et al.The 2007 WHO classification of tumours of the central nervous system[J].Acta neuropathologica,2007,114(2):97-109.
  • 8Christy P,Tervonen O,Scheithauer B,et al.Use of a neural network and a multiple regression model to predict histoiogic grade of astrocytoma from MRI appearances[J].Neuroradiology,1995,37(2):89-93.
  • 9王忠诚.神经外科学[M].2版.北京:人民卫生出版社,2006:541-548.
  • 10Burnet N,Lynch A,Jefferies S,et al.High grade glioma:imaging combined with pathological grade defines management and predicts prognosis[J].Radiother Oncol,2007,85(3):371-378.

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