β-磷酸三钙的加入对玻璃基生物骨水泥显微结构的影响

Effect of β-TCP to the microstructure of glass based bioactive bone cement

目的探讨β-磷酸三钙(β-TCP)的加入对玻璃基生物骨水泥显微结构的影响。方法以CaHPO4·2H2O和CaCO3为原料,采用固相反应法制备β-TCP,并将其掺入到玻璃基生物骨水泥中制成复合骨水泥,浸泡在模拟体液(simulated body fluid,SBF)溶液中,研究其显微结构的变化。结果通过湿式粉碎和固相反应法可以制得晶体发育良好、纯度高的β-TCP粉末;复合骨水泥试样中的β-TCP在SBF溶液的浸泡下会逐步降解,从而制得具有较高孔隙率的骨水泥。结论随β-TCP掺加量的增加,骨水泥试样的显气孔率增加,体积密度降低。

Objective To explore the effect of β-TCP to the microstmcture of glass based bioactive bone cement. Methods The β-TCP was prepared through the method of solid state reaction by using dicalcium phosphote and calcium carbonate as starting materials. The composite bone cement which was made up of β-TCP and glass based bioactive bone cement was immersed in the simulated body fluid and its microstructure and morphology were investigated. Results The results demonstrate that full-fledged, high pure β-TCP can be prepared by the method of wet pulverizing and solid state reaction, that the porous bone cement can be prepared by the degradation of β-TCP in the composite bone cement. Conclusion Addition of β- TCP and apparent porosity of the bone cement is increased, the bulk density will decrease.