多种因素对卵母细胞浆内单精子显微注射结果影响的探讨

The Analysis of Effectiveness on Intracytoplasmic Sperm Injection with Multiple Factors

目的：研究进行卵母细胞浆内单精子显微注射（ICSI）过程中诸多因素的影响。方法：对263个周期行ICSI的患者的各种因素,包括不孕原因、促排方案、精液来源及质量等进行受精率、卵裂率、优质胚胎率及妊娠率的比较。结果：男方因素合并女方PCOS、附睾穿刺获得精子、HMG方案、取卵数目介于20-30及月经第3天血E2浓度对优质胚胎的获得有影响,但是对妊娠率没有明显的影响。结论：所观察、研究的各种因素对妊娠率影响不明显。

Objective： To observe the effect of multiple factors on Intracytoplasrnic sperm Injection programme. Methods： A total of 263 consecutive cycles were included. To compare multiple factors including the reason of infertility, COH protocols, the resource and quality of sperm on the fertilization rate, cleavage rate, good quality embryo rate and pregnancy rate.Results： The multiple factors had significant effect on obtaining good quality embryo but had not significant effect on pregnancy rate.Conclusions：It＇s feasible to apply Intracytoplasmic sperm Injection technique to ART. The multiple factors have no significant effect on pregnancy rate.