摘要
帕金森病(Parkinson’s disease,PD)常见于中老年人,临床表现为静止性震颤、肌僵直、运动迟缓和平衡障碍等,病理特征是中脑黑质纹状体系统多巴胺(DA)能神经元变性死亡。虽然其病因还不是完全清楚,也没有治愈该病的方法,但合理的治疗仍可使患者较长时间地保持工作和生活自理能力。本文就PD当前治疗状况及进展作一介绍。
出处
《神经损伤与功能重建》
2007年第6期359-361,共3页
Neural Injury and Functional Reconstruction
参考文献23
-
1罗毅.原发性帕金森病治疗的建议[J].中华老年医学杂志,1999,18(3):133-134. 被引量:16
-
2AMES BN, SHIGENAGA MK, HAGEN TM. Oxidants, Antioxidants, and the Degenerative Diseases of Aging[J]. Proc Natl Acad Sci USA(S1091-6490),1993,90:7915-7922.
-
3SANCHEZ-RAMOS J, OVERVIK E, AMES B. A Marker of Oxyradieal-mediated DNA Damage (8-hydroxy-2-deoxyguanosine) Is Increased in Nigro-striatum of Parkinson's Disease Brain[J]. Neurodegeneration( S1055 - 8330), 1994,3 : 197 - 204.
-
4OLANOW CW, WATTS RL, KOLLER WC. An Algorithm (decision tree) for the Management of Parkinson's Disease (2001) : Treatment Guidelines[J]. Neurology(S0028-3878), 2001,56(suppl 5) :S1 -S88.
-
5BIGLAN KM, SCHWID S, EBERLY S, et al. Rasagiline Improves Quality of Life in Patients with Early Parkinson's Disease[J]. Mov Disord(S0885-3185) ,2006,21(5) :616-623.
-
6CI.ARKE CE. Rasagiline for Motor Complications in Parkinson's Disease[J]. Lancet(S0023-7507),2005, 365(9463): 914-916.
-
7HRISTOVA AH, KOLLER WC. Early Parkinson's Disease: What Is the Best Approach to Treatment[J]. Drug & Aging (S1170-229X),2000,17(3) :165- 181.
-
8KONDO T. Initial Therapy for Parkinson's Disease: Levodopa vs. Dopamine Receptor Agonists[J]. J Neurol(S0340-5354), 2002, 249 (Suppl 2): Ⅱ25-Ⅱ29.
-
9ZIEGLER M, CASTRO-CALDAS A, DEL SIGNORE S, et al. Efficacy of Piribedil as Early Combination to Levodopa in Patients with Stable Parkinson's Disease: A 6-month, Randomized, Placebo-controlled Study[J]. Mov Disord (S0885 - 3185),2003,18(4):418-425.
-
10SHANNON KM, BENNETT JP , FRIEDMAN JH. Efficacy of Pramipexole, a Novel Dopamine Agonist, as Monotherapy in Mild to Moderate Parkinson ' s Disease. The Pramipexole Study Group [J]. Neurology( S0028-3878), 1997,49 (3) : 724 - 728.
二级参考文献22
-
1[2]Lozano A,Hutchison W,Kiss Z,Tasker R,Davis K, Dostrovsky J.Methods for microelectrode guided posteroventral pallidotomy. J Neurosurg 1996;84(2):194- 202
-
2[3]Gross RE, Lombardi WJ, Hutchison WD,et al.Variability in lesion location after microelectrode guided pallidotomy for Parkinson's disease: anatomical,physiological,and technical factors that determine lesion distribution.J Neurosurg 1999;90(3):468- 77
-
3[4]Chihiro Ohye.Use of selective thalamotomy for various kinds of movement disorder,based on basic studies.Stereotact Funct Neurosurg 2000;75:54- 65
-
4[5]Limousin P,Pollak P,Benazzouz A,et al.Effect of parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation.Lancet 1995;345:91- 5
-
5[6]Sala F,Krzan MJ,Deletis V.Intraoperative neurophysiological monitoring in pediatric neurosurgery:why, when, how? Childs Nerv Syst 2002;18(6- 7):264- 87
-
6[7]Peyron R,Garcia LL,Deiber M,et al.Laurent Electrical stimulation of precentral cortical area in the treatment of central pain: electrophysiological and PET study.Pain 1995;62(3): 275- 86
-
7[8]Wennberg R,Arruda F,Quesney LF,Olivier A.Preeminence of extrahippocampal structures in the generation of mesial temporal seizures: evidence from human depth electrode recordings.Epilepsia 2002;43(7):716- 26
-
8[9]Van Roost D, Solymosi L, Schramm J, van Oosterwyck B, Elger CE.Depth electrode implantation in the length axis of the hippocampus for the presurgical evaluation of medial temporal lobe epilepsy:a computed tomography based stereotactic insertion technique and its accuracy.Neurosurgery 1998;43(4):819- 26
-
9[10]Moriarty TM,Kikinas R,Jolesz FA,Black P McL,Alexander E.Magnetic resonance imaging therapy.Intraoperative imaging.Neurosurg Clin North Am 1996;7:323- 7
-
10[11]Chu RM,Tummala RP,Kucharczyk J,Truwit CL,Maxwell RE.Minimally invasive procedures.Interventional MR image guided functional neurosurgery.Neuroimaging Clin N Am 2001;11(4):715- 25
共引文献21
-
1郭丽娜.原发性帕金森病的治疗概述[J].中国临床康复,2004,8(19):3891-3891. 被引量:1
-
2于新,刘宗惠,周东学,亓树彬,钟强,崔月汉,于雪,林伟,胡向红,周正谋,王大鹏.功能神经外科的选择:OUR-XGD旋转式伽玛刀放射生物学效应(英文)[J].中国临床康复,2004,8(28):6222-6225.
-
3刘春杰,董立珉,刘郁.中西医结合治疗帕金森病[J].时珍国医国药,2006,17(3):428-429. 被引量:10
-
4邵明.帕金森病的现代治疗与进展[J].临床内科杂志,2006,23(6):375-377. 被引量:3
-
5林健,邱宝安.晚期胰腺癌所致神经性疼痛的机制与对策[J].海军总医院学报,2006,19(2):102-105. 被引量:3
-
6邓顺周,李润铭.帕金森病治疗药物[J].食品与药品,2007,9(05A):28-31. 被引量:3
-
7耿百乐,闫志兰,田军彪,李哲,顾平.抗颤宁方对帕金森病模型大鼠纹状体单胺类神经递质含量的影响[J].河北中医,2009,31(2):278-280. 被引量:3
-
8常鹏飞.我国功能神经外科的发展现状和机遇[J].中国医师杂志,2011,13(1):142-144. 被引量:3
-
9付萍萍,严菊俏,麦思美,钟慧娉.认知行为疗法对癫痫所致精神障碍的治疗效果[J].国际护理学杂志,2012,31(7):1218-1220. 被引量:6
-
10石林,杨岸超,孟大伟,刘焕光,张颖,张鑫,张建国.斜向立体定向穿刺法与垂直立体定向穿刺法的对比研究[J].立体定向和功能性神经外科杂志,2012,25(6):349-351.
同被引文献41
-
1罗叶容,巫纪英,黄连珠,李化机,陆玉枝.老年痴呆症护理者的心理调适[J].当代护士(中旬刊),2005,12(2):61-62. 被引量:2
-
2李蓉.癌症患者家属心理需求的调查分析[J].福州总医院学报,2004,11(F07):23-24. 被引量:1
-
3李菲菲,费立鹏,阎德亮,孟梅,李兰英.首发精神分裂症病人家属心理问题与家庭干预的对照研究[J].现代护理,2005,11(1):10-12. 被引量:13
-
4张红星,赵靖平,张玉娟,吕路线,李文强,张燕.重性精神病患者一级亲属的心理状况分析[J].中国行为医学科学,2006,15(9):824-826. 被引量:9
-
5冯洪,谢家兴,李秋红,张红云,邱红.脑卒中患者家属心理健康水平及其影响因素[J].中国康复理论与实践,2006,12(8):679-681. 被引量:13
-
6王连芝,曹秀萍,王秀兰.癌症患者女性家属心理状况调查[J].齐鲁护理杂志,2006,12(10A):1921-1922. 被引量:8
-
7邹红,付莹,孔海燕.重症监护患者家属心理健康问题的调查研究[J].重庆医学,2007,36(8):761-763. 被引量:5
-
8常恩荣,胡建荣,刘爱英.肿瘤患者家属心理状态的健康教育干预[J].齐鲁护理杂志,2006,12(10B):2065-2066. 被引量:4
-
9Trend P,Kaye J,Gage H,et al.Short-term effectiveness of intensive multidisciplinary rehabilitation for people with Parkinson ' s disease and their carets.Clin Rehabil,2002,16 (7):717-25.
-
10Edwards NE,Scheets PS.Predictors of burden for caregivers of patients with Parkinson' s disease.J Neurosci Nurs,2002,34(4):184-90.
引证文献3
-
1卢慧芳.帕金森患者家属身心健康状况的研究进展[J].中华现代护理杂志,2010,16(11):1359-1360. 被引量:2
-
2卢慧芳,王红,高钰琳.居家帕金森病患者家属照顾者的生活质量调查及分析[J].护理管理杂志,2011,11(3):176-178. 被引量:8
-
3刘旺,赵虹,夏兆云,刘慧瑛,陆征宇.帕金森病相关病理演变研究进展[J].神经损伤与功能重建,2022,17(3):148-151. 被引量:12
二级引证文献22
-
1陈爱民,贾艳梅,秦红英.晚期艾滋病患者家属生活质量影响因素调查及对策[J].中国误诊学杂志,2011,11(21):5290-5291. 被引量:1
-
2邾萍,付菊芳,郭丝锦,黄颖,王花,杨华.乳腺癌患者男性照顾者照顾体验的质性研究[J].解放军护理杂志,2012,29(15):9-12. 被引量:23
-
3朱迎,林征,丁霞芬,卞秋桂.肝硬化失代偿期患者主要照顾者的健康状况及其影响因素分析[J].中国实用护理杂志,2013,29(7):62-64. 被引量:13
-
4何菁,龚丝语,徐筱春.社区居家帕金森病患者安全措施的建立与实施[J].上海护理,2014,14(3):71-73. 被引量:9
-
5易萍.心理干预对老年痴呆患者照顾者积极感受及悲伤情绪的影响[J].当代护士(上旬刊),2016,23(4):144-146. 被引量:10
-
6陈虹宇,宋宇,付宪秋.居家帕金森患者主要照顾者照顾负担与疲劳状况的相关性分析[J].中华现代护理杂志,2016,22(3):350-352. 被引量:14
-
7于金华,徐雪英.家庭护理干预对降低居家帕金森病患者药物漏服的影响[J].临床医药文献电子杂志,2017,4(2):316-316.
-
8汪丹,刘佳,崔倩,李艳丽.帕金森合并抑郁症的临床分析及护理对策探讨[J].中国医药科学,2017,7(18):151-153. 被引量:1
-
9张世西,何月月,尹安春,黄秀美,刘思雨.帕金森病患者照顾者照护体验质性研究的Meta整合[J].护理学报,2020,27(22):45-51. 被引量:9
-
10柳竹,苏东宁,刘亘梁,王雪梅,王展,马惠姿,冯涛.早发型帕金森病患者体位性低血压的危险因素[J].神经损伤与功能重建,2022,17(6):328-332. 被引量:2
-
1邵明.帕金森病的现代治疗与进展[J].临床内科杂志,2006,23(6):375-377. 被引量:3
-
2潘天鸿,任光辉,周金方,杨德平,王文明.高血压脑出血57例手术治疗体会[J].实用临床医药杂志,2004,8(4):89-90. 被引量:1
-
3黄继忠,张明园.非典型抗精神病药治疗精神分裂症的评价(一)[J].上海精神医学,2005,17(4):230-232. 被引量:3
-
4罗祖明.急性脑梗死的现代治疗[J].四川医学,2002,23(6):551-553. 被引量:1
-
5姜佐宁.惊恐障碍的现代治疗[J].中华结核和呼吸杂志,2001,24(9):514-515. 被引量:5
-
6张希廉,田军彪,李玉森.帕金森病的现代治疗研究[J].中西医结合心脑血管病杂志,2008,6(8):991-992. 被引量:1
-
7康淑华.癫痫的现代治疗[J].中国现代医生,2008,46(13):44-45. 被引量:3
-
8罗祖明.脑出血的现代治疗[J].实用医院临床杂志,2004,1(1):5-6.
-
9刘吉梅,刘吉欣.脑心通胶囊结合西药治疗脑血管病临床观察[J].中国现代药物应用,2009,3(14):125-126. 被引量:3
-
10黄光祥,孙军.阿托伐他汀对进展性脑梗死患者神经功能的影响[J].中国基层医药,2013,20(8):1127-1128. 被引量:1