摘要
目的：比较替硝唑和甲硝唑治疗滴虫性阴道炎的疗效。方法：６０例滴虫性阴道炎病人，随机单盲分为２组。替硝唑组３０例，年龄３３±ｓ５ａ（２２～５１ａ），用替硝唑治疗，首日顿服２．０ｇ，ｄ２，ｄ３各顿服１．０ｇ，疗程３ｄ。甲硝唑组３０例，年龄３６±７ａ（２０～５２ａ），用甲硝唑０．２ｇ，ｐｏ，ｔｉｄ，疗程７ｄ。结果：替硝唑组和甲硝唑组总有效率分别为８７％和８０％，２组疗效比较无显著差异（Ｐ＞０．０５），但不良反应发生率分别为２３％和７０％，有显著性差异（Ｐ＜０．０１）。结论：替硝唑治疗滴虫性阴道炎疗程短，不良反应小。
AIM: To compare tinidazole (Tin) and metronidazole(Met) in treating Trichomonas vaginitis. METHODS: Sixty patients with Trichomonas vaginitis were randomly divided into 2 groups. Thirty patients (age 33±s 5 a) received orally Tin 2.0 g on the 1 st day, 1.0 g on d 2 and d 3. The other 30 patients (age 36±7 a) received orally Met 0.2 g, tid for 7 d. RESULTS: The total effective rates in Tin and Met groups were 87% and 80%, respectively(P>0.05). Their adverse reaction rates were 23% and 70%, respectively (P< 0.01). CONCLUSION: Tin better than Met in treating Trichomonas vaginitis.
出处
《新药与临床》
CSCD
北大核心
1997年第4期219-220,共2页
