摘要
目的:比较替硝唑和甲硝唑治疗滴虫性阴道炎的疗效。方法:60例滴虫性阴道炎病人,随机单盲分为2组。替硝唑组30例,年龄33±s5a(22~51a),用替硝唑治疗,首日顿服2.0g,d2,d3各顿服1.0g,疗程3d。甲硝唑组30例,年龄36±7a(20~52a),用甲硝唑0.2g,po,tid,疗程7d。结果:替硝唑组和甲硝唑组总有效率分别为87%和80%,2组疗效比较无显著差异(P>0.05),但不良反应发生率分别为23%和70%,有显著性差异(P<0.01)。结论:替硝唑治疗滴虫性阴道炎疗程短,不良反应小。
AIM: To compare tinidazole (Tin) and metronidazole(Met) in treating Trichomonas vaginitis. METHODS: Sixty patients with Trichomonas vaginitis were randomly divided into 2 groups. Thirty patients (age 33±s 5 a) received orally Tin 2.0 g on the 1 st day, 1.0 g on d 2 and d 3. The other 30 patients (age 36±7 a) received orally Met 0.2 g, tid for 7 d. RESULTS: The total effective rates in Tin and Met groups were 87% and 80%, respectively(P>0.05). Their adverse reaction rates were 23% and 70%, respectively (P< 0.01). CONCLUSION: Tin better than Met in treating Trichomonas vaginitis.
出处
《新药与临床》
CSCD
北大核心
1997年第4期219-220,共2页