聚甲酚磺醛治疗子宫颈糜烂100例

Policresulen in treating cervical erosion in 100 patients

目的：观察聚甲酚磺醛治疗子宫颈糜烂的效果。方法：１００例子宫颈糜烂病人，于月经后３～７ｄ内先以聚甲酚磺醛浓缩液（１ｇ浓缩液含聚甲酚磺醛３６０ｍｇ）纱布敷在宫颈糜烂处，每次３ｍｉｎ，隔日１次共２次，次日用聚甲酚磺醛栓剂１枚（每枚含９０ｍｇ）塞入阴道深处，隔日１次共６次为一个疗程。结果：单纯型、颗粒型、乳突型宫颈糜烂显效率分别为９０％，３１％和１０％，三者相比，Ｐ＜０．０１，对轻型宫颈糜烂的疗效较中、重度为好。６例病人用药局部有烧灼感。结论：聚甲酚磺醛对单纯型或轻型子宫颈糜烂的疗效好。

AIM: To verify the efficacy of policresulen in treatment of cervical erosion. METHODS: During 3-7 d after the menstrual period, 100 women with cervix erosion were treated with the gauze soaked with concentrated policresulen liquid (1 g liquid contained 360 mg policresulen) laid on the affected area for 3 min, qod 2 times, and following the policresulen suppository (contained policresulen 90 mg) were inserted deeply into the vagina qod 6 times. The reexamination was done after the next mense. RESULTS: The remarkable response rates of the simple, granular, and papilary types were 90%, 31%, and 10%, respectively, P<0.01. Marked response rates of policresulen on cervical erosion of mild, moderate, and severe degree were 87%, 59%, and 15%, respectively, P<0.05. Six patients complained of burning feeling in vagina during medication.CONCLUSION: Policresulen is very efficient for the treatment of simple and mild cervical erosion.