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肝细胞癌的间质化疗 被引量:1

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摘要 目前肝癌治疗是以手术为主的综合治疗,但总的手术切除率仅为20%~30%,因此化疗是肝癌治疗的重要辅助手段。但传统的静脉化疗虽有一定的效果,但全身不良反应较大,病人往往难以耐受。因此,改变给药途径,即通过局部或区域性给药,能大大提高肿瘤区域内化疗药物的浓度,增加化疗药物对肿瘤细胞的直接细胞毒性作用,并有效地降低全身不良反应。随着抗肿瘤药物缓释剂型的技术改进和对给药途径的观念更新,区域性化疗即腹腔内化疗、肝动脉灌注化疗、门静脉灌注化疗、间质化疗等方法,日益成为治疗肝癌的有效方法及手段。
出处 《外科理论与实践》 2007年第6期601-603,共3页 Journal of Surgery Concepts & Practice
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