摘要
目的探讨不稳定性心绞痛患者经皮冠状动脉介入术(PCI)后血浆肌钙蛋白I(cTnI)对预后的预测价值。方法选择172例单支病变接受PCI术的不稳定性心绞痛患者,术后24h抽取静脉血化验cTnI,观察12～25个月的严重心脏不良事件。结果术后cTnI升高组(n=51)的严重心脏不良事件明显高于术后cTnI正常组(17.65%vs7.44%,P<0.05),cTnI升高组的血脂水平、他汀类药物、植入支架枚数、球囊预扩张时间、术前hsCRP水平与cTnI正常组比较,差异有统计学意义。结论cTnI的升高对PCI术后患者的预后有着重要的影响,尽早、足量的他汀类药物以及关注炎症的相关指标可使病人获益更大。
Objective To evaluate the value of cardiac troponin Ⅰ （ CTnⅠ） for predicting the prognosis in patients after percutaneous coronary intervention （PCI）. Methods CTnⅠ was monitored 24 h after procedure in 172 patients with unstable angina who underwent PCI in the single branch lesion. Major cardiovascular events （MACE） were recorded in 12 - 25 months of follow-up. Results The occurrence rate of MACE in group with increased cTnⅠ was significantly higher than in normal one. There was a significant difference in hyperlipidemia, statin, the number of stents,total inflation time and higher high-sensitivity C-reactive protein between CTnⅠ increase group and normal group. Conclusion CTnⅠ increase after procedure effects MACE in follow-up. High-intensity statin and attention of the role of systemic inflammation may be useful for patients after PCI.
出处
《内科》
2007年第6期878-880,共3页
Internal Medicine
关键词
肌钙蛋白Ⅰ
经皮冠状动脉介入术
预后
Cardiac troponin Ⅰ
Pereutaneous coronary intervention
Prognosis
