骨髓间充质干细胞的活体标记示踪技术及其研究进展

Living labeling techniques of mesenchymal stem cells

骨髓基质干细胞因具有不断自我更新和向多种细胞分化的能力而备受关注。通过干细胞移植并诱导其向各种受损组织细胞分化，可促进受损组织的再生和修复，为疾病的治疗开辟了新途径。为更深入认识移植细胞实现其修复功能的机制，需要有效的标记方法追踪移植细胞在受者体内的分布、迁移、增殖和分化情况。

Mesenchymal stein cells （MSCs） are well known for their self-renew and multidifferentiation potentiality. With the transplantation of the MSCs which can promote the regeneration and repair of the injured tissue, a new route for the treatment of dieases is hopeful to be effective. To trace the distribution, migration, proliferation and differentiation of the implanted MSCs, there need effective labeling techniques, especially living labeling techniques.