针灸治疗带状疱疹后遗神经痛文献质量评价

Evaluation of the Quality of Reports on Acupuncture for Treating Postherpetic Neuralgia

目的对针灸治疗带状疱疹后遗神经痛的文献进行质量评价。方法电子检索MEDLINE、CBM、CMCC及CNKI1994～2006年研究文献,并手工检索《中国针灸》等中文期刊及其它未发表文献。对文献研究类型及方法学、一般情况、疾病诊断及纳入和排除标准、疗效判定标准、样本含量估计、随访等方面进行评价。结果纳入的109篇研究中,真正随机对照试验的仅6个;半随机对照试验17个;非随机同期对照试验13个;病例对照研究1个;叙述性研究63个;有明确诊断标准者29个;提及纳入或排除标准者14个;有明确疗效标准者79个;有随访记录者24个;仅1篇文献提及不良反应。结论以往发表的针灸治疗带状疱疹后遗神经痛的高质量研究文献较少。今后应开展高质量、前瞻性、多中心大样本的随机对照试验。

Objective To assess the quality reports on acupuncture in the treatment of postherpetic neuralgia. Methods MEDLINE, CBM, CMCC and CNKI from 1994 to 2006 were searched electronically. Handsearching was also done. The retrieved articles were assessed in terms of several factors, including the type of clinical research, methodology, diagnostic criteria, inclusion/exclusion criteria, effectiveness measurements, calculation of sample size, follow-up, etc. Results Among the 109 included articles, only 6 were true randomized controlled trials. There were 17 quasi-randomized controlled trials, 13 non-randomized concurrent controlled trials, 1 case-control study and 63 narrative studies. 29 of the reports clearly described the diagnostic criteria, 14 mentioned the inclusion/exclusion criteria, 79 reported the effectiveness measurements, none mentioned the calculation of sample size, 24 reported the follow-up outcomes, and only 1 mentioned adverse reactions. Conclusion More prospective, multicenter, large-scale, high-quality randomised trials are needed, and recommendations should also be made for future evaluations of methodological quality.