摘要
[目的]了解深圳龙岗地区沙门菌的流行特点和耐药情况。[方法]对从本地区2003~2007年食物中毒和伤寒,副伤寒疫情中分离的67株沙门菌进行纸片扩散法(K-B法)药敏实验。[结果]沙门菌主要流行菌群为D群,以引起食物中毒最常见,食物中毒占总暴发疫情的40.30%,51.85%食物中毒由肠炎沙门菌引起;沙门菌对氟哌酸,氯霉素,氨基糖苷类及第3代头孢类抗生素完全敏感,对青霉素,苯唑西林完全耐药,头孢氨苄的耐药率高达41.79%,对氨苄西林,羧苄西林,哌拉西林,四环素和复方新诺明的耐药率达到了37.31%,37.31%,25.37%,25.37%和2.99%;非伤寒沙门菌对羧苄西林,氨苄西林,强力霉素,四环素,哌拉西林,美满霉素的耐药率显著性的高于伤寒和副伤寒沙门菌;沙门菌多重耐药率为13.00%。[结论]沙门菌引起的暴发疫情在逐年增加,其对除四环素,氨苄西林,羧苄西林,哌拉西林和复方新诺明外其他常用抗生素都敏感,非伤寒沙门菌的耐药性在显著增加。
[Objective]To investigate the epidemic characteristics and drug-resistant status of salmonella in Longgang district of Shenzhen[Methods]67 strains of salmonella isolated from patients with food-poisoning,typhoid fever and paratyphoid fever from 2003 to 2007 in Longgang district were conducted susceptibility test by using Kirby Bauer disk diffusion method(K-B method) .[Results]The epidemic flora of salmonella was D type salmonella,which common induced food-poisoning.Food poisoning accounted for 40.30% in all the communicable diseases caused by salmonella,51.85% of the patients with food-poisoning was caused by salmonella enteritidis.Salmonella showed completely sensitivity to norfloxacin,chloromycin,aminoglycosides and the third generation cephalosporin antibiotics,and showed completely drug-resistance to penicilling and oxacillin.The drug resistant rates of Salmonella for ampligram,ampicillin,carbenicillin,piperacillin,tertracycline and bactrim were 41.79%,37.31%,37.31%,25.37%,25.37% and 2.99%,respectively.The drug resistance of non-typhoid bacillus for ampicillin,carbenicillin,vibramycin,tetracycline,piperacillin and minomycin detected to be significantly higher than that of typhoid and paratyphoid bacillus.The multiple antibiotic resistant rate of salmonella was 13.00%.[Conclusion]The outbreaks of infectious diseases caused by salmonella increase year by year,and salmonella shows sensitivity to the common antibiotics except ampicillin,carbenicillin,piperacillin,tertracycline and bactrim,while the drug resistant of non-typhoid bacillus is significantly increased.
出处
《现代预防医学》
CAS
北大核心
2007年第24期4654-4656,共3页
Modern Preventive Medicine
关键词
沙门菌
食物中毒
抗生素耐药性
Salmonellae
Food-poisoning
Antibiotic-resistance