郑州市小儿呼吸道病毒性感染病原学初析

Analysis of the pathogeny of virus infection in children's respiratory track.

目的探讨本市小儿呼吸道病毒性感染的病原学分布现状,为防治工作提供资料。方法应用ELISA法检测患儿急性期血清中7种病毒(IV、PIV、RSV、ADV、CBV、EBV、MP)特异性IgM抗体,以了解病原学分布。结果从8 594例被检患儿血清中,检出相关IgM抗体阳性2 907例,总阳性率为34.0%。含单一病毒感染占85.6%,2种混合感染占14.4%。单一病毒感染中IV占首位(29.4%),其余依次为MP(21.0%)、ADV(14.3%)、RSV(13.1%)、PIV(12.9%)、EBV(4.7%)、CBV(4.6%)。结论IV、MP、ADV、RSV、PIV为本地致小儿呼吸道感染的主要流行病原体。3岁前(新生儿除外)因免疫力低,对各种病毒的易感率高,故需关注此年龄段的预防工作。对疑似病例作IgM检测,能及时提供病原学诊断依据,并可作为流行病学调查的信息资料。

Objective To explore the distribution condition of virus infection in children＇s respiratory track this city, to provide evidence for prevention. Methods to detect the special IgM antibody of 7 kinds of virus （ IV, PIV, RSV, ADV,CBV, EBV,MP） by using ELISA. Results the serum antibody IgM of 2907 from 8549 children were positive. The total positive rate was 34%, among them signal virus infection 85.6% , 2 kinds of virus infection 14.4%. IV is the first cause of single infection（ 29.4% ） , in turn MP （21%）, ADV（14.3%）, RSV（13.1%）, PIV（12.9%）, EBV（4.7%）, C BV（4.6%）. Conclusions -IV, MP, ADV, RSV, PIV are the primary prevalent pathogeny of children＇s respiratory infection this area. Children below 3 years old exception neonate are easy to be infected, so they should be paid more attention for prevention. The suspect cases should be detected IgM to provide the diagnosis evidence.