丁座草的化学成分研究

Chemical constituents of Boschniakia himalaica

目的研究丁座草Boschniakia himalaicaHook.f.et Thoms.块茎的化学成分。方法采用柱色谱分离,通过理化性质和光谱分析确定化合物的结构。结果与结论从丁座草块茎的乙醇提取物中,共分离得到7个化合物,鉴定了5个化合物,分别为3β-乙酰熊果酸(3β-acetoxyurs-12-en-28-oic acid,Ⅰ)、3β-乙酰齐墩果酸(3β-acetyloleanolic acid,Ⅱ)、β-谷甾醇(β-sitosterol,Ⅲ)、熊果酸(ursolic acid,Ⅳ)、(+)-松脂素单葡萄糖苷[(+)-pinoresinol monoglucoside,Ⅴ]。化合物Ⅰ为首次从该属植物中分离得到,化合物Ⅱ和Ⅲ为首次从该植物中分离得到。

Aim To investigate the chemical constituents in the barks of Boschniakia himalaica Hook. f. et Thorns. Methods The constituents were isolated and purified by column chromatography and their structures were elucidated on the basis of physicochemical properties and spectral analysis, Results and conclusion Seven compounds were isolated from the ethanol extract of B. himalaica and five compounds were identified as 3β-acetoxyurs-12-en-28-oic acid （ Ⅰ ）, 3β-acetyloleanolic acid （ Ⅱ ）, fl-sitosterol （ Ⅲ ）, ursolic acid （ Ⅳ）, and （ ＋ ）-pinoresinol monoglucoside （ Ⅴ ）, respectively. Compound Ⅰ is isolated from this genus for the first time. Compounds Ⅱ and Ⅲ are isolated from this plant for the first time.