Y染色体SNP和STR多态在人类学研究中的应用

Application of Y-chromosome SNP and STR in Anthropology Research

在人类群体遗传学研究中,Y染色体非重组区多态(特别是单核苷酸多态性和短串联重复序列)由于具有许多优势,发挥着其他标记无法替代的重要作用,因而是研究群体起源和迁移的理想工具。通过对Y染色体非重组区多态及其在人类学中应用价值的研究,尤其对Y染色体单核苷酸多态性和短串联重复序列的特点进行的综合分析,认为Y染色体非重组区多态在鉴别民族的起源和迁移研究中具有较大的准确度和可操作性,必将继续发挥巨大作用。

Polymorphisms of the non-recombining regions of Y-chzornosome （especially mononneleotide polymorphism and short tandem repeats （STR）） is exerting an important effect that can not be replaced by any other markers because of its ninny advantages, so it is an ideal instruments in studying origin and migra- tion of human populations. Studies of Y-chromosome non-recombining regions and its application value on an- thropology, especially the general analysis of the characteristics of Y-chromsome SNP and STR, showed that polymorphisms of the non-recombining regions of Y-chromosome had more accuracy and manipuility in distin- guishing ethnical origin and migration, nhich will play more important role in future.