磁共振动态增强扫描在垂体微腺瘤诊断中的价值

The value of dynamic contrast enhancement MRI in the diagnosis of pituitary micro adenoma

目的:评估MRI动态增强扫描的检查质量和其在垂体微腺瘤诊断中的价值。方法:分析经临床及实验室检查诊断为垂体微腺瘤38例的MRI平扫、钆喷替酸葡甲胺动态增强扫描及常规延迟增强扫描图像,判断钆喷替酸葡甲胺动态增强扫描图像质量,以及统计MRI平扫、钆喷替酸葡甲胺动态增强扫描及常规延迟增强扫描检出率。结果:MRI平扫、动态增强扫描及常规延迟增强扫描对病灶检出分别16例(42.1%)、34例(89.5%)、26例(68.4%)。3种不同的扫描方法病灶检出率差异有统计学意义(P<0.05)。结论:MRI钆喷替酸葡甲胺动态增强扫描是相对简单、易行、成功率高的检查方法,可明显提高垂体微腺瘤的检出率,可作为MRI诊断垂体微腺瘤的常规检查方法。

Objective ：To evaluate the examinational quality of dynamic contrast enhancement MRI and its effect in diagnosing pituitary microadenoma. Methods ：The data of 38 cases with pituitary microadenoma confirmed by clinical manifestation and biochemical tests were studied by plain MRI, Gd-DTPA dynamic enhanced MRI and conventional delayed enhanced MRI. To evaluate the quality of image of Gd-DTPA dynamic enhanced MRI ,and statistics the rate of lesion detection of plain MRI, Gd-DTPA dynamic enhanced MRI and conventional delayed enhanced MRI. Results ：The positive rate in Gd-DTPA dynamic enhanced MRI was 100%, the positive rate of diagnosis for pituitary micro adenoma with plain MRI scan, dynamic enhanced MRI and conventional delayed enhanced MRI was 42.1%（16/38）, 89.5%（34/38） and 68.4%（26/38） respectively, and there were statisticaly significances（P〈0.05 ）among different scanning methods. Conclusion：Gd-DTPA dynamic enhanced MRI was relatively simple, easy, efficientand obviously improved its detection rate. Dynamic enhanced MRI should be considered as the conventional examinational method in diagnosing pituitary microadenoma.