超声引导下经直肠前列腺癌穿刺活检PSA及外腺体积研究

PSA and volume of external gland in ultrasound-guided biopsy of prostatic carcinoma

目的:探讨超声引导下经直肠前列腺穿刺活检术临床应用的价值及PSA和前列腺外腺体积与前列腺癌病变之间的关系。方法:超声引导下经直肠前列腺穿刺活检320例,观察和统计PSA≤410μg/L和PSA>410μg/L时前列腺癌的检出率;对前列腺癌组和良性病变组两组体积进行统计分析。结果:PSA≤410μg/L和PSA>410μg/L时前列腺癌的检出例数分别为17例和98例,两组前列腺癌的检出率比较差异有统计学意义(P<0.05)。前列腺体积在前列腺癌和良性病变比较差异无统计学意义(P>0.05),但外腺体积在两者之间差异有统计学意义(P<0.05)。结论:前列腺血清特异抗原(PSA)及外腺体积是指导超声引导下经直肠前列腺穿刺活检术筛查的重要指标。

Objective ：To study clinical value of ultrasound-guided biopsy of prostate gland and the relationship between prostatic carcinoma and relevant factors such as PSA and volume of external gland. Methods：320 cases who had underwent ultrasound-guided prostatic biopsy by rectal approach were summarized,of which detection rates of prostatic carcinoma （in different PSA groups, namely PSA ≤410 and 〉410 μg/L）were observed, of which the volume of prostate were significant difference （in different groups,namely prostatic carcinoma and benign lesion）. Results：The people of prostatic cancer in PSA≤410 and 〉410 μg/L were 17 and 98 respectively and there were statistical significance in detection rates between two groups （P〈0.05）.There were not statistical significance in volume of prostate （P〉0.05）, but there were statistical significance in volume of external gland （P〈0.05）.Conclusions：Relevant factors of prostatic carcinoma such as PSA and volume of external gland are the important guide for prostatic biopsy.