期刊文献+

来曲唑与克罗米酚用于多囊卵巢综合征60例促排卵疗效比较 被引量:4

下载PDF
导出
摘要 目的:将来曲唑与克罗米酚分别用于多囊卵巢综合征(PCOS)60例,比较来曲唑及克罗米酚对卵泡发育及子宫内膜的影响。方法:选择PCOS 60例随机分成两组,各30例,均于月经来潮或撤退性出血第3~5天口服来曲唑2.5 mg与克罗米酚100 mg,观察来曲唑与克罗米酚对卵泡发育及子宫内膜的影响。结果:出现优势卵泡来曲唑组26例,克罗米酚组11例(P<0.05);单卵泡发育来曲唑组22例,克罗米酚组3例(P<0.05);HCG注射日子宫内膜厚度来曲唑组9.92±1.51 mm,克罗米酚组5.86±0.92 mm(P<0.01)。结论:来曲唑促排卵效果好,单卵泡发生率高,降低卵巢过度刺激综合征、多胎妊娠的发生率。
作者 丁家怡
出处 《南通大学学报(医学版)》 2007年第6期521-522,共2页 Journal of Nantong University(Medical sciences)
  • 相关文献

参考文献4

二级参考文献47

  • 1Furbass R, Kalbe C, Vanselow J. Tissue-specific expression of the bovine aromatase-encoding gene uses multiple transcriptional start sites and alternative first exons. Endocrinology, 1997, 138:2813-2819.
  • 2Huang JC, Liu DY, Yadollahi S, et al. Interleukin-1 beta induces cyclooxygenase-2 gene expression in cultured endometrial stromal cells. J Clin Endocrinol Metab,1998,83:538-541.
  • 3Kitawaki J, Koshiba H, Ishihara H, et al. Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium. J Clin Endocrinol Metab, 2000,85:3292-3296.
  • 4Arvanitis DA, Koumantakis GE, Goumenou AG, et al. CYP1A1, CYP19, and GSTM1 polymorphisms increase the risk of endometriosis. Fertil Steril, 2003,79 Suppl 1:702-709.
  • 5Fang Z, Yang S, Gurates B, et al. Genetic or enzymatic disruption of aromatase inhibits the growth of ectopic uterine tissue. J Clin Endocrinol Metab, 2002,87:3460-3466.
  • 6Takayama K, Zeitoun K, Gunby RT, et al. Treatment of severe postmenopausal endometriosis with an aromatase inhibitor. Fertil Steril, 1998,69:709-713.
  • 7Ailawadi RK, Jobanputra S, Kataria M, et al. Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. Fertil Steril, 2004,81:290-296.
  • 8Waller KG, Shaw RW.Gonadotropin-releasing hormone analogues for the treatment of endometriosis: long-term follow-up. Fertil Steril, 1993 59:511-555.
  • 9Shozu M, Sumitani H, Segawa T, et al. Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leuprorelin acetate. J Clin Endocrinol Metab, 2001, 86:5405-5411.
  • 10Shozu M, Murakami K, Segawa T, et al. Successful treatment of a symptomatic uterine leiomyoma in a perimenopausal woman with a nonsteroidal aromatase inhibitor.Fertil Steril, 2003,79:628-631.

共引文献62

同被引文献23

  • 1王玉真,刘卫红.克罗米芬对多囊卵巢综合征患者着床期子宫内膜的影响[J].中国妇幼保健,2004,19(12):55-56. 被引量:6
  • 2朱亮,邢福祺.促排卵临床应用进展[J].生殖与避孕,2007,27(7):488-493. 被引量:14
  • 3Badawy A,Aal I A,Abulatta M.Clomiphene Citrate or Letrozole for Ovulation Induction in Women with Polycystic Ovarian Syndrome:a Prospective Randomized Trial[J].Fertil Steril,2009,92(3):849-852.
  • 4Baruah J,Roy K K,Rahman S M,et al.Endometrial eVects of Letrozole and Clomiphene Citrate in Women with Polycystic Ovary Syndrome Using Spiral Artery Doppler[J].Arch Gynecol Obstet,2009,279:311-314.
  • 5Bayar U,Basaran M,Kiran S,et al.Use of an Aromatase Inhibitor in Patients with Polycystic Ovary Syndrome:a Prospective Randomized Trial[J].Fertil Steril,2006,86(5):1447-1451.
  • 6Atay V,Cam C,Muhcu M,et al.Comparison of Letrozole and Clomiphene Citrate in Women with Polycystic Ovaries Undergoing Ovarian Stimulation[J].J Int Med Res,2006,34:73-76.
  • 7Robert F, Casper MD, Letrozole. Ovulation or supper ovulation?[J]. Fertility and Sterility, 2003,80(6) : 1335.
  • 8Mitwally MF, Casper RF. Use of an aromatase inhibitor for inducting of ovulation in patients with an inadequate response to clomipheng citrate [J].Fertil Steril, 2001, 75 (2) : 305.
  • 9Cortinez A, De Carvalho I, Vantman D. Hormonal profile and endometrial morphology in letrozole controlled ovarian hyperstimulation in ovulatory infertile patients [J].Fertil Steril, 2005, 83:110.
  • 10罗丽兰,黄荷凤.不孕不育[M].北京:人民卫生出版社,2009:259-279.

引证文献4

二级引证文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部