肾动脉狭窄患者相关危险因素分析

Relative Risk Factors of Patients with Renal Artery Stenosis

目的探讨动脉粥样硬化性肾动脉狭窄(ARAS)患者的相关危险因素及与肾功能的关系。方法选取ARAS患者64例,分析其临床资料,并选取36例肾动脉正常者为对照。结果肾动脉狭窄组与对照组相比,冠心病、冠状动脉多支病变、外周血管疾病、肾功能不全的发病率增高(P<0.05),年龄、脉压、肌酐、尿素氮水平明显升高(P<0.01)。结论高龄、冠心病、冠状动脉多支病变、宽脉压、外周血管疾病及肾功能不全为ARAS患者的危险因素;严重的肾动脉狭窄可导致肾功能不全。

Objective To study the risk factors of patients with atherosclerotic renal artery stenosis （ARAS） and the relation with renal function. Methods The renal function of 64 ARAS patients was measured and compared with 36 healthy controls. Results Compared with the healthy controls, the incidence rates of morbilities of coronary artery disease, more than single-vessel, peripheral vascular disease, renal inadequacy increased significantly （P 〈0. 05）, and the age, pulse pressure, levels of blood urea nitrogen （BUN）, serum creatinine （SCr） were significantly higher （ P 〈0.01） in ARAS patients. Conclusion The elder, coronary artery disease, more than single-vessel, large pulse pressure, peripheral vascular disease and renal inadequacy are risk factors for ARAS. Severe renal artery stenosis may lead to renal inadequacy.