525例围手术期患者预防性应用抗菌药物的调查分析

Survey of perioperative antimicrobial administration in 525 cases

采用回顾性调查方法，对2006年3～4月本院外科手术病例应用抗菌药物的品种、用药频度、联合用药情况、用药时间等方面进行调查，其中525例围手术期患者抗菌药物的应用率为92．00％，选用的药物以氟喹诺酮类和三代头孢类抗菌药物为主；预防用药时间平均为4．5天／人，术前给药103例（占21．32％），其中术前2h以上给药占94．2％，术后给药380例（占78．67％）。围手术期抗菌药物预防性应用在种类选择、用药时机和持续时间等方面存在不合理现象，围手术期抗菌药物的使用需进一步规范。

Retrospective survey was made to investigate the current status of the perioperative use of antimicrobials in patients of our hospital. Among registered 525 surgical patients during Mar. - Apr. 2006, perioperative use of antimicrobials accounted for 92.00%. Of all antimicrobials used, quinolones and the third-generation cephalosporins were used most frequently. The mean antimicrobial course was 4.5 d personally. It is very important to strengthen and improve the management of antimicrobials use in surgeries.